a Cancer Research UK Cambridge Institute, Cambridge Biomedical Campus, UK b Department of Medical Biophysics, University of Toronto, Canada c Informatics and Bio-Computing Program, Ontario Institute for Cancer Research, Toronto, Canada d Bioinformatics Unit, Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University London, UK e Centre for Cancer Research and Cell Biology (CCR...

Peter W. Collins, Elizabeth Chalmers, Daniel P. Hart, Ri Liesner, Savita Rangarajan, Kate Talks, Mike Williams and Charles R. Hay School of Medicine, Cardiff University, University Hospital of Wales, Wales, Royal Hospital for Sick Children, Glasgow, The London School of Medicine and Dentistry, Royal London Hospital, Barts, Queen Mary University, London, Great Ormond Street NHS Trust, London, Ha...

Detection and quantification of Hb subtypes of human blood is integral to presumptive identification of thalassaemias. It has been used in neonatal screening of thalassaemia and Hb variants. The use of discarded red blood cells following processing of the cord blood for stem cells provides readily available diagnostic material for thalassaemia screening. In this study, we determined the range o...

We have used high-throughput small RNA sequencing to characterize viral small RNA expression in purified tonsillar B and T lymphocytes isolated from patients tested positive for Epstein-Barr virus (EBV) or human adenovirus (HAdV) infections, respectively. In the small set of patients analyzed, the expression profile of EBV and HAdV miRNAs could not distinguish between patients diagnosed with to...

Abstract Memory phenotype (MP) CD4 T cells that develop in the absence of overt antigen stimulation are important for both innate and adaptive immune responses. Although pathogen specific MP have been found to function effectively against infection, it is not known if Tfh can also be developed stimulation. Here, we demonstrate In addition FR4+, a mark induced memory cells, expressed high levels...