Two hybrid bacteriocins, enterocin E50-52/pediocin PA-1 (EP) and pediocin PA-1/enterocin E50-52 (PE), were designed by combining the N terminus of enterocin E50-52 and the C terminus of pediocin PA-1 and by combining the C terminus of pediocin PA-1 and the N terminus of enterocin E50-52, respectively. Both hybrid bacteriocins showed reduced MICs compared to those of their natural counterparts. ...

conclusions it was found that the isolated bacteria produced biosurfactants that had a great potential for different industries. results the 3 isolates from cheese, yoghurt and silage were effective against isolated e.coli and could produce biosurfactants. phylogenic relationships of the 3 potential candidates were determined comparing the 16sr dna gene sequences, they were found to be as 3 iso...

Abstract Background Bacteriocins are generally defined as ribosomally synthesized peptides, which produced by lactic acid bacteria (LAB) that affect the growth of related or unrelated microorganisms. Conventionally, extracted bacteriocins purified precipitation, where ammonium sulphate is added to precipitate out protein from solution. Main text To achieve high purity bacteriocins, a combinatio...

Preservation of food and beverages resulting from fermentation has been an effective form of extending the shelf-life of foods for millennia. Traditionally, foods were preserved through naturally occurring fermentations, however, modern large scale production generally now exploits the use of defined strain starter systems to ensure consistency and quality in the final product. This review will...

The aim of this research work was to identify and characterized the bacteriocins produced by soil-associated bacteria. Bacillocin from Bacillus brevis Bb and pyocin from Pseudomonas aeruginosa Pa were found bioactive only against gram-positive bacteria tested. Maximum production of both the bacteriocins was observed at 32 degrees C in BHI medium. Production of both the bacteriocins started in t...

Lysostaphin is an antimicrobial agent belonging to a major class of antimicrobial peptides and proteins known as the bacteriocins. Bacteriocins are bacterial antimicrobial peptides which generally exhibit bactericidal activity against other bacteria. Bacteriocin production is a self-protection mechanism that helps the microorganisms to survive in their natural habitats. Bacteriocins are current...

Introduction Antibiotics have been used as therapeutic and prophylactic treatments to control a variety of bacterial infections in livestock for more than 50 years. Different types of antibiotics have also been fed at sub-therapeutic levels to cattle, poultry and swine to increase productivity and feed efficiency (McDermott et al., 2002). The emergence of antibiotic-resistance in many bacteria ...

The discovery of penicillin by Fleming in 1928 was an historical milestone in the fight against infectious disease. Over the following fifty years, pharmaceutical companies discovered and developed over 100 antibiotics effective against a wide range of human pathogens. More recently, the dramatic rise in antibiotic-resistant pathogens has stimulated renewed efforts to identify, develop or redes...

Bacteriocins are natural peptides secreted by several bacteria that exert bactericidal activity against other bacterial species. Research in this topic is promoted not only by the need to develop alternatives to antibiotics and drugs that have shown non-desirable effects, but also to the capacity of some bacteriocin to inhibit saprophytic and food-borne pathogens in food stuffs. Many LAB are ba...

This work had as main objectives to characterize two bacteriocins produced by lactic acid bacteria (LAB) previously isolated from non-fermented seafood, in order to evaluate their potential as new food protective agents. The two bacteriocinogenic isolates were identified by Polymerase Chain Reaction (PCR) using genus- and species-specific primers, and confirmed by 16S rDNA sequencing, as Entero...