(1) Proteolytic digests of tissue elastin contain material which reacts with dimethylaminobenzaldehyde in acid solution (Ehrlich's reagent) to give a cherry-pink colour. This Ehrlich chromogen(s) [EC(s)] is similar to but not identical with EC(s) previously demonstrated in tissue collagens [Scott, Hughes & Shuttleworth (1979) Biosci. Rep. 1, 611-618]. Both ECs react with diazonium salts in acid...

Reduced graphene oxide-azobenzene (RGO-AZO) hybrids were prepared via covalent functionalization for long-term solar thermal storage. Thermal barrier (ΔEa) of cis to tran reversion and thermal storage (ΔH) were improved by molecular hydrogen bonds (H-bonds) through ortho- or para-substitution of AZO. Intramolecular H-bonds thermally stabilized cis-ortho-AZO on RGO with a long-term half-life of ...

Introduction Azo dyes – a fatal threat or a new generation of drugs? In 1858 Griss developed the azo coupling reaction and obtained first azo dye – Aniline Yellow. Nowadays, around 10 thousands of these compounds are described and more than 2 thousands are applied to color various materials. Azo dyes are characterized by the presence of the azo moiety (–N=N–) in their structure, conjugated with...

A multifunctional gold nanorod (AuNR) complex is described with potential utility for theranostic anticancer treatment. The AuNR was functionalized with cyclodextrin for encapsulation of doxorubicin, with folic acid for targeting, and with a photo-responsive dextran-azo compound for intracellular controlled drug release. The interaction of a AuNR complex with HeLa cells was facilitated via a fo...

The title compound, [RuCl(C10H14)(C11H10N4)]Cl is an Ru(II) complex in which an η (6) -p-cymene ligand, two N atoms of 3-amino-2-(phenyl-azo)pyridine and one Cl ion form a piano-stool coordination environment around the metal ion. In the crystal structure, N-H⋯Cl hydrogen bonds play an important role in the formation of the supramolecular zigzag chain along the a-axis direction. Disorder is obs...

2-(1-(4-Bromophenyl)-2-thiocyanatoethylidene)malononitrile (3) undergoes azo coupling with diazotized aromatic amines to afford arylhydrazone derivatives, which are readily cyclized to afford the corresponding 3(2H)-pyridazinimine derivatives upon reflux in aqueous NaOH. Under similar condition an o-cyanoarylhydrazone derivative was cyclized into 6H-pyridazino[1,6-a]quinazolin-6-imine, which in...

A new method has been developed to synthesise bis η(5)-cyclopentadienyl dithiolene complexes of molybdenum and tungsten. This procedure involves the in situ thermolysis of the azo compounds, 2,2'-azobisisobutyronitrile (AIBN) or 1,1'-azobiscyclohexanecarbonitrile (ACCN) (R'(2)N(2), R' = CMe(2)CN or C(6)H(10)CN, respectively), which initiates a reaction between [Cp(2)M(S(4))] (M = Mo or W) and a...

Hydroxytriazenes behave like bidentate ligands which have alpha hydroxyl group relative to azo group. The synthesis includes reduction of an alkyl or aryl nitro compound in neutral medium to get hydroxylamine and diazotization of an aromatic amine to get diazonium chloride. When these two that is hydroxylamine and respective diazonium salt are coupled we get hydroxytriazene as a product. A gene...

The crystal structure of the title compound, C14H14N2O, determined at 293 K, shows that the molecule is approximately planar in the solid state and that the aromatic rings have a trans configuration with respect to the azo double bond, as found for other diazene derivatives. The packing can be described as a polymeric arrangement of molecules linked through O-H...N and C-H...O hydrogen bonds an...

Approximately 0.7 million tons of azo dyes are synthesized each year. Azo dyes are composed of one or more R₁-N=N-R₂ linkages. Studies have shown that both mammalian and microbial azoreductases cleave the azo bonds of the dyes to form compounds that are potentially genotoxic. The human gastrointestinal tract harbors a diverse microbiota comprised of at least several thousand species. Both water...