BACKGROUND COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal permeability barrier (EPB) establishment during development, similar to what was observe...

THE VALUABLE EMPHASIS ON MODERNITY in colonial and postcolonial African studies has profoundly divided precolonial African history from what comes after. But the depth and complexity of African aspirations for moral community and the forms of collective action they inspire, often in the face of severe material constraints, exceed the explanatory power of narratives of modernity oriented toward ...

Cartilage is a tissue with limited self-healing potential. Hence, cartilage defects require surgical attention to prevent or postpone the development of osteoarthritis. For cell-based cartilage repair strategies, in particular autologous chondrocyte implantation, articular chondrocytes are isolated from cartilage and expanded in vitro to increase the number of cells required for therapy. During...

Strain hardening cementitious composite (SHCC) is a special class of ultra-ductile material which has autogenous self-healing capability due to its intrinsic tight crack widths. To further improve healing ability, agent (HA) can be incorporated in SHCC, enabling it also the autonomous mechanism. In this study, effects adding bacteria-embedded polylactic acid (PLA) capsules on mechanical propert...

a chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time or wounds that do not heal within three months are often considered chronic. chronic wounds often remain in the inflammatory stage for too long and may never heal or may take years. chronic wound patients often report pain as dominant in their lives. persistent pain is the main problem ...

background a combination of the oils of sesame, hemp, wild pistachio, and walnut has been used for treatment of skin disorders, including wound burns, in some parts of kerman, iran. evaluation of this remedy in the form of a pharmaceutical formulation in animal models can pave the way for its future application in wound burn healing in humans. conclusions a new therapeutic remedy was introduced...

to understand the traditional description of medicine as a practice of healing, it is necessary to examine its relationships with both science and ethics. the “scientific” component of medicine includes an acknowledgment of the influence of social, cultural and environmental factors on the functioning of the organism. the “ethical” component is often presented as merely supplementary but actual...

background different methods for dressing of donor site of skin graft in burn patients have similarly pain, limitation of mobility of donor site and local complications such as infection and scar. amniotic membrane has used for improvement of healing in some wounds. accordingly in this study amnion was used as biologic dressing for donor site of skin graft to evaluate it’s efficacy in improveme...