BACKGROUND Parents of seriously ill children participate in making difficult medical decisions for their child. In some cases, parents face situations where their initial goals, such as curing the condition, may have become exceedingly unlikely. While some parents continue to pursue these goals, others relinquish their initial goals and generate new goals such as maintaining the child's quality...

Designing for better user experiences (e.g., interactions more satisfying, enjoyable) is usually more difficult than aiming for clearer usability goals (e.g., improve systems’ efficiency, easy of use). In this paper, we present a conceptual model validated with data from 603 mobile phone users that clarifies the relationship between usability of basic mobile services and the users’ satisfaction...

The Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole genome sequences of representatives from all eukaryotic species on earth. In addition the Project’s technical and organizational challenges, it also faces complicated ethical, legal, social issues. This paper, members EBP’s Ethical, Legal, Social Issues (ELSI) Committee, catalogs these ELSI concerns arising EBP. While we...

Kamphof offers an illuminating depiction of the technological mediation of morality. Her case serves as the basis for a plea for modesty up and against the somewhat heroic conceptualizations of techno-moral change to date-less logos, less autos, more practice, more relationality. Rather than a displacement of these conceptualizations, I question whether Kamphof's art of living offers only a dif...

1. Dept. of Molecular Diagnosis, Armin Pathobiology Laboratory, Tehran, Iran 2. Baqiyatallah Research Center for Gastroenterology and Liver Disease, Baqiyatallah University of Medical Sciences, Tehran, Iran 3. Dept. of Gynecology-Oncology, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran 4. Dept. of Gynecology-Oncology, Erfan Hospital, Tehran, Iran 5. Dept. of Gynecology...

1Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran 2Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, USA *Corresponding author: Hoda Javadikasgari, Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Vali-Asr St., Niayesh Blvd, ...

Current evidence indicates that conventional mechanical ventilation often leads to lung inflammatory response and oxidative stress, while lung-protective ventilation (LPV) minimizes the risk of ventilator-associated lung injury (VALI). This study evaluated the effects of LPV on relief of pulmonary injury, inflammatory response, and oxidative stress among patients undergoing craniotomy. Sixty pa...

BACKGROUND Communication gaps impact the quality of patient care. Previous research has focused on communication barriers rather than seeking solutions. Our aim was to identify strategies for effective communication and decision-making about goals of care for medical interventions in serious illness, from the perspectives of hospital-based healthcare providers. METHODS A cross-sectional surve...

BACKGROUND Patient-centered care requires knowledge of patients' goals of care (GoC) on the part of health care providers (HCPs). Whether HCPs caring for in-center hemodialysis patients meet this criterion is uncertain. OBJECTIVE We designed and conducted a GoC survey among patients and HCPs within a single in-center hemodialysis (ICHD) program to determine whether HCPs have an understanding ...

BACKGROUND Postgraduate medical trainees are not well prepared difficult conversations about goals of care with patients and families in the acute care clinical setting. While contextual nuances within the workplace can impact communication, research to date has largely focused on individual communication skills. Our objective was to explore contextual factors that influence conversations betwe...