squamous cell carcinoma (scc) of the buccal mucosa accounts for 23% to 37% of all intraoral cancers, the prognosis is generally poor. we reported a case of local invasion of buccal squamous cell carcinoma. a 32-year-old man referred to the clinic with a chief complaint of swelling in the right cheek region that initiated from 6 months ago and rapidly grow from one month ago. history of the pati...

background: invasive squamous cell carcinoma of the vulva is primarily a disease of postmenopausal women and thus is rarely associated with pregnancy. case: we have reported on a young woman under 40 years old with vulvar carcinoma, which occurred during the pregnancy but optimal treatment was delayed to the postpartum period. this 37-year-old woman was diagnosed with 3x3 cm vulvar lesion, 2 we...

patients. in this disease the risk of many malignancies is increased, of which the most important is non- hodgkin lymphoma of the small intestine. other malignancies include adenocarcinoma of the small intestine and squamous cell carcinoma of the esophagus. to the best of our knowledge, thus far only one case of celiac disease associated with hypopharyngeal squamous cell carcinoma has been repo...

background: lung cancer ranks among the most common and most lethal malignancies worldwide. once vascular or lymphatic invasions occur, metastatic dissemination to distant sites is common. bone, liver, adrenals, and brain are the most frequent sites of the distant disease. in this study we present a case of squamous cell carcinoma of lung with metastasis of the left knee bursa.case presentation...

BACKGROUND p16 (INK4a) (p16) is a well-recognized surrogate molecular marker for human papilloma virus (HPV) related squamous dysplasia. Our hypothesis is that the invasive interventions and related morbidities could be avoided by objective stratification of positive cytologic interpretations by p16 immunostaining of cell block sections of cytology specimens. MATERIALS AND METHODS Nuclear imm...

The Cellient Automated Cell Block System (Hologic) can be used to process cervical scrapes to paraffin sections. For the first study on this subject, cervical scrapes were fixed in the formalin-free fixative BoonFix. This pilot study was limited to cases classified as atypical squamous lesion of unknown significance (ASCUS) and high-grade squamous lesion (HSIL) as diagnosed in the ThinPrep slid...

Mucins are cell bound high molecular weight glycoproteins which secreted by epithelial cells. Total 21 mucin variants identified till date. Mucin1 (MUC1) is a transmembrane glycoprotein, when reacts with beta-catenin, can able to enter the nucleus activate T-cell factor/leukocyte enhancing factor 1 transcription factors and gene expression, after it may inhibit cell-cell cell-stroma interaction...

Background & Objective: This study aimed to examine the extent which postcoital bleeding (PCB) can be a predictive factor for cervical cancer. Materials Methods: In this observational we selected and evaluated 280 females with PCB referred Kowsar Hospital of Qazvin, Iran from 2017 2019. Results: Among 189 patients diagnosed as normal in their Pap smear results, one patient had cancer her b...

OBJECTIVE Evaluate the relationships between AgNORs polymorphisms and squamous intraepithelial lesions (SIL) and squamous cell carcinoma (SCC) with HPV infection. MATERIALS AND METHODS A study was carried out on sixty women from the state of Guerrero, Mexico. HPV detection was performed by PCR. AgNORs were identified by argentic impregnation. One hundred cells per slide were counted and class...

background: the aim of this study was to present epidemiological aspects of malignant tumor of head and neck in southeast of iran, with a view toward analyzing the age, gender, site distribution and histological types.  methods: all cases with malignant tumor of the head and neck region from 1999 to 2009 were retrieved from the records of cancer registry center of kerman university of medical s...