BACKGROUND Family size and high birth order were related to the prevalence of hayfever and positive skin prick test. However, this association may be explained by maternal atopy. We examined the relationship between maternal atopy and the number of offspring in three European cohorts of pregnant women. METHODS The mothers and their children (n = 1487) were recruited for the Asthma Multi-centr...

Alcohol-based hand rubs are used frequently in healthcare settings, but their tolerance among atopic subjects is unknown. The dermal tolerance to five alcohol-based hand rubs was assessed among atopic and non-atopic subjects in a repetitive occlusive patch test. In total, 54 subjects were analysed. One half of the subjects were atopic (modified Erlanger atopy score > or = 8), the other half wer...

OBJECTIVES We investigated the relationship between breastfeeding, asthma and atopy, and child body mass index (BMI). METHODS From a prospective birth cohort (n = 2860) in Perth, Western Australia, 2195 children were followed up to age 6 years. Asthma was defined as doctor-diagnosed asthma and wheeze in the last year, and atopy was determined by skin prick test of 1596 children. Breastfeeding...

Abstract A 29-year-old woman of Lithuanian heritage was referred to dermatology with a 3-year history recurrent blistering the hands and, occasionally, feet. The patient’s own photographs revealed small, tense blisters on sides her fingers and one foot. In general clinic, she noted have acrylic nails, which had been applying at home gel nail kit for over 5 years. recent years, patient noticed t...

BACKGROUND AND AIM: We sought to carry out a systematic review and meta-analysis of the diagnostic value of ‎epicutaneous patch testing in patients with oral lichenoid lesions (OLLs).‎ METHODS: Bibliographic searches were conducted in electronic databases such as PubMed, the Cochrane library, ‎EBSCO, Scopus, Web of knowledge and Google scholar from January 1990 to December 2011. Search terms re...

Methods A total number of 127 patients from Outpatient Allergic Clinic MED-ALL Medical Centre (age 2-76 years old) with suspected ACD were examined using the most common allergens from the patch tests from the European Standard Series including nickel, pallatium, chrome, cobalt, fragrance-mix I and II, balsam of Peru, formaldehyde and propolis and one extra allergen – house dust mite (HDM). The...

BACKGROUND The atopy patch test (APT) is an in vivo model to study the induction of eczema by inhalant allergens in atopic dermatitis (AD) patients. Mepolizumab is a monoclonal antibody to interleukin-5, which reduces peripheral blood eosinophils. Previously, we reported that mepolizumab treatment did not result in clinical improvement in AD. The current study investigates the effect of mepoliz...

BACKGROUND Several risk factors for the development of asthma and atopic disease in children have been described. Furthermore, there is consistent evidence that the prevalence of atopy increases with higher socioeconomic status. The knowledge about risk factors and preventive factors for atopy needs to be improved. OBJECTIVE To compare 2 child populations (foster care and reference children) ...