Atopic dermatitis is a chronic inflammatory skin disease characterized by impaired epidermal barrier function, inflammatory infiltration, extensive pruritus and a clinical course defined by symptomatic flares and remissions. The mechanisms of disease exacerbation are still poorly understood. Clinical occurrence of atopic dermatitis is often associated with psychological stress. In response to s...

VIDAL (1886) first described cataract in young patients subject to attacks of pruritis followed by lichenification and associated with asthma. Andogsky (1914) described four cases of unclassified skin disease with cataract as 'dermatogenous cataract', and Kugelberg (1934) used the term 'syndermatotic juvenile cataract'. Brunsting (1936) reported ten cases of atopic dermatitis with juvenile cata...

This study attempts to determine the incidence of contact allergy in children in Hong Kong and to see if any difference in the incidence of contact allergy exists between children with non-atopic and atopic dermatitis. It also attempts to identify the common contact allergens for children in Hong Kong. 217 children under 16 were classified into non-atopic and atopic dermatitis groups and there ...

The United Kingdom Working Party diagnostic criteria for atopic dermatitis have been characterized in infants and children; however, the need for visual confirmation of flexural dermatitis by a trained investigator limits their use in large epidemiologic studies. We have administered the complete United Kingdom Working Party criteria in a postal questionnaire format to the mothers of year old i...

OBJECTIVES Major objective is the evaluation of the medical effectiveness of different therapeutical approaches and the cost effectiveness with relevance for Germany. METHODS This health technology assessment (HTA) evaluates systemically randomized controlled studies (RCT) on the therapy of atopic dermatitis which were published between 1999 and 2004. Further it includes some important clinic...

Background: Studies suggest that low concentrations of n–6 long-chain polyenes in early life are correlated to atopic disease in later life. Objective: The purpose of the study was to investigate the possible preventive effect of -linolenic acid (GLA) supplementation on the development of atopic dermatitis in infants at risk. Design: In a double-blind, randomized, placebo-controlled trial, form...

BACKGROUND Atopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence. Because of the significant socioeconomic effect of atopic dermatitis and its effect on the quality of life of children and families, there have been decades of research focused on disease prevention, with limited success...

Background and aim: Atopic dermatitis (AD) is a chronic disorder that is most common in early childhood. Both immunological and psychological factors are important in AD pathogenesis and should therefore be taken into account. The aim of this study was to compare behavioral characteristics of 30 infants (3-12 month-old) with AD with 40 controls.Materials and Methods: Th...

This guideline is an update from August 2020 the S2k-guideline “Atopic dermatitis” published in 2015. The reason for updating this chapter of were current developments field systemic therapy atopic dermatitis. agreed recommendations treatment dermatitis present are based on scientific data. Due to approval dupilumab moderate severe dermatitis, which cannot be treated sufficiently with topical d...

Atopic dermatitis is a chronic inflammatory skin condition including severe pruritus, xerosis, visible eczematous skin lesions that mainly begin early in life. Atopic dermatitis exerts a profound impact on the quality of life of patients and their families. The estimated lifetime prevalence of atopic dermatitis has increased 2~3 fold during over the past 30 years, especially in urban areas in i...