OBJECTIVE Both type 1 diabetes (T1D) and celiac disease (CD) have been linked to autoimmune thyroid disease (ATD). We examined if individuals with both T1D and CD were at a higher risk of ATD than those with only T1D. RESEARCH DESIGN AND METHODS This study was a nationwide population-based cohort study. We defined T1D as having an inpatient or a hospital-based outpatient diagnosis of T1D at a...

A significant obstacle to developing high performance Deep Learning algorithms for Automated Threat Detection (ATD) in security X-ray imagery, is the difficulty of obtaining large training datasets. In our previous work, we circumvented this problem for ATD in cargo containers, using Threat Image Projection and data augmentation. In this work, we investigate whether data scarcity for other moda...

Because of the lack of pediatric biomechanical data, the Hybrid-III (HIII) child anthropomorphic test devices (ATDs) are essentially scaled from the mid-size male ATD, and are often criticized for its rigid spine comparing to those from children. In this study, possible design modifications for improving the spine biofidelity of the HIII 6-year-old ATD were explored by child cadaver/volunteer t...

BACKGROUND The neurotransmitter serotonin (5-HT) has been linked to the underlying neurobiology of aggressive behavior, particularly with evidence from studies in animals and humans. However, the underlying neurobiology of aggression remains unclear in the context of attention-deficit/hyperactivity disorder (ADHD), a disorder known to be associated with aggression and impulsivity. We investigat...

BACKGROUND The therapeutic options to treat Alzheimer-type dementia (ATD) in recent years, have made it increasingly necessary to become familiar with the employment pattern of these new medicinal products. METHODS A cross-sectional observational study of the population with ATD treated with acetylcholinesterase inhibitors and/or memantine in the Gallician Health Service. Databases were compi...

We present results of a nonperturbative Floquet study of above-threshold detachment (ATD) of the H – and F – negative ions. Pronounced enhancements of ATD rates in the high-energy plateau region are found as the laser field intensity passes across ponderomotively shifted multiphoton thresholds. Depending on the symmetry of the initial state ( s or p symmetry), the enhancement is found to be mos...

HLA and Gm typing were carried out in 16 families. Seven families included 10 sib pairs with rheumatoid arthritis (RA) and autoimmune thyroid disease (ATD) respectively, and nine families included 16 sib pairs with RA and circulating thyroid autoantibodies respectively. Eight, 11, and seven sib pairs with either RA or clinical or immunological evidence of ATD shared none, one, and two HLA haplo...

A variety of experimental evidence suggests that rapid, long-range propagation of conformational changes through the core of proteins plays a vital role in allosteric communication. Here, we describe a non-equilibrium molecular dynamics simulation method, anisotropic thermal diffusion (ATD), which allowed us to observe a dominant intramolecular signaling pathway in PSD-95, a member of the PDZ d...

The following report outlines the design guidelines associated with ATD: The Autonomous Test Driver. ATD’s design allows it to quickly navigate a walled course, utilizing fast integrated sensors to accurately detect the course and to a rudimentary job in learning to navigate the course. After a slow first traversal of a course, when ATD learns the required sequence and locations of turns, on su...