نتایج جستجو برای: assisted laser desorption

تعداد نتایج: 307043  

Journal: :Optics express 2001
D Bauer F Ceccherini

Time-dependent density functional theory (TDDFT) is employed to study the interaction of a Ne atom with short and strong 800\,nm laser pulses. In the intensity regime covered (10;14-10;16 W/cm;2) up to triply ionized Ne is observed. Good quantitative agreement with the experimental Ne;+ ion-yield (and the Ne;2+ -yield near saturation) is obtained. Nonsequential ionization (NSI) leads to a stron...

Journal: :The Analyst 2012
Hongmei Yang Ming Li Zongjun Li Shuying Liu

Laser-enhanced in-source decay (LEISD) MALDI MS recently proposed for structural analysis of oligosaccharides was used to systematically investigate ISD fragmentation of oligosaccharides, which was found to be mediated by thermal hydrogen radicals from a matrix and underwent a charge-induced process, depending on the nature of the matrix and the structure of an oligosaccharide.

Journal: :The Analyst 2006
Richard Knochenmuss

Matrix Assisted Laser Desorption/Ionization (MALDI) is a very widely used analytical method, but has been developed in a highly empirical manner. Deeper understanding of ionization mechanisms could help to design better methods and improve interpretation of mass spectra. This review summarizes current mechanistic thinking, with emphasis on the most common MALDI variant using ultraviolet laser e...

Journal: :Physical review letters 2010
H Kang W Quan Y Wang Z Lin M Wu H Liu X Liu B B Wang H J Liu Y Q Gu X Y Jia J Liu J Chen Y Cheng

We present energy-resolved angular distributions of photoelectrons generated in above-threshold ionization (ATI) of nonaligned diatomic molecules N2 and O2 in high-intensity short laser pulses, with emphasis on the most energetic part of the spectra. The angular distribution for photoelectrons with energy of 10U(p) (U(p): ponderomotive energy), i.e., the plateau cutoff in ATI spectra, is found ...

Journal: :Accounts of chemical research 2017
David E Clemmer David H Russell Evan R Williams

While non-native protein conformations such as folding intermediates are rarely observed in solution such species are often stabilized as gaseous ions during electrospray ionization for mass spectrometry. This opens the possibility of large scale efforts to capture information about many non-native structures such as folding intermediates or malformed conformations having deleterious effects: s...

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