how to cite this article: aggarwal a, mittal h, debnath skr, rai a. neuroimaging in cerebral palsy–report from north india. iran j child neurol. 2013 autumn; 7(3):41- 46.   objective only few indian reports exist on neuroimaging abnormalities in children with cerebral palsy (cp) from india.   materials & methods we studied the clinico-radiological profile of 98 children diagnosed as cp at a ter...

BACKGROUND AND PURPOSE Hydroxyethyl starch (HES) has beneficial effects on ischemic brain injury; however, its mechanism of action remains unclear. The present study was undertaken to test the hypothesis that HES can attenuate increases in leukocyte adherence and vascular permeability in the cerebral vasculature after global cerebral ischemia induced by asphyxia. METHODS Pial venular leukocyt...

The risk of asphyxia by polythene bags is well recognised and such bags carry a warning against children using them as toys. We report an instance of near-fatal asphyxia in a 2-year-old child by a "shopping bag" being accidentally pulled over her head. The bag was made of polyvinylchloride and cotton and is sold for use by children (see figure).

Perinatal asphyxia constitutes a prototype of obstetric complications occurring when pulmonary oxygenation is delayed or interrupted. The primary insult relates to the duration of the period lacking oxygenation, leading to death if not re-established. Re-oxygenation leads to a secondary insult, related to a cascade of biochemical events required for restoring proper function. Perinatal asphyxia...

OBJECTIVES To compare the Conventional, Specified, Expanded and Combined Apgar scoring systems in predicting birth asphyxia and the adverse early neurologic outcomes. METHODS This prospective cohort study was conducted on 464 admitted neonates. In the delivery room, after delivery the umbilical cord was double clamped and a blood samples was obtained from the umbilical artery for blood gas an...

We examined mitochondrial oxidative function 5 minutes and 2 hours after a gradual asphyxial insult in newborn lambs. We subjected 16 ventilated newborn lambs to 75-90 minutes of hypoxia and hypercarbia that resulted in bradycardia and systemic hypotension over the final 15 minutes of the insult. At the end of asphyxia, the lambs were resuscitated and returned to control ventilator settings. Sa...

A resumption of, and escalation in, breathing efforts (hyperpnoea) reflexively accelerates heart rate (HR) and may facilitate cardiac and circulatory recovery from apnoea. We analysed whether this mechanism can produce a sustained rise in HR (tachycardia) when a sleeping infant is confronted by mild, rapidly worsening asphyxia, simulating apnoea. Twenty-seven healthy term-born infants aged 1-8 ...

MR scans of 25 patients who suffered asphyxia at known gestational ages were reviewed retrospectively. The gestational ages of the patients at the time of asphyxia ranged from 24 to 46 weeks. The MR pattern of brain damage in patients with prolonged partial asphyxia was seen to evolve in a predictable manner corresponding to the known maturation of the brain and its vascular supply. Patients at...