PURPOSE To determine if a scrape injury to cat corneal endothelial cells increases the level of mitogenic proteins such as transforming growth factor alpha (TGF alpha) in aqueous humor. METHODS Aqueous humor of cats was collected at 0, 2, 6, and 24 hours after wounding the endothelium by contact with a cannula tip. Aqueous humor samples collected from sham-wounded cats served as controls. Aqu...

PURPOSE To investigate the aqueous humor proteome in patients with glaucoma and a control group. METHOD Aqueous humor was obtained from five human donors diagnosed with primary open angle glaucoma (POAG) and five age- and sex-matched controls undergoing cataract surgery. Quantitative proteome analysis of the aqueous humor by hyper reaction monitoring mass spectrometry (HRM-MS) based on SWATH ...

The aim of the present study was to examine whether humor styles mediated the associations between the pathological forms of narcissism (grandiose narcissism and vulnerable narcissism) and self-esteem in a sample of Israeli undergraduates (N = 200). Grandiose narcissism was positively associated with the use of adaptive humor (i.e., self-enhancing humor and affiliative humor), whereas vulnerabl...

In this article some formal, content-related and procedural considerations towards the sense of humor are articulated and the analysis of both everyday humor behavior and of comic styles leads to the initial proposal of a four factormodel of humor (4FMH). This model is tested in a new dataset and it is also examined whether two forms of comic styles (benevolent humor and moral mockery) do fit i...

PURPOSE To determine whether aqueous humor promotes cell death in cells involved in inflammatory responses. METHODS Multiple immune cell types, most characteristically involved in inflammatory responses, were incubated for 24, 48, and 72 hours in the presence or absence of 50% aqueous humor. Promotion of cell death was assayed by staining for an early indicator of apoptosis. The percentage of...

PURPOSE The structures of the ocular anterior segment responsible for aqueous humor secretion and absorption have been well characterized in mammals. However, the underlying molecular and cellular mechanisms that regulate aqueous humor flow have remained elusive. Experimental analysis in Danio rerio, the zebrafish, is providing mechanistic insights into many cellular processes relevant to norma...