Abstract Myocarditis is an inflammatory disease of the myocardium with either focal or diffuse involvement and usually gives rise to chest pain, dyspnea, palpitations, fatigue. In severe cases, arrythmias, syncope, cardiogenic shock may occur. Acute myocarditis most commonly caused by a variety viruses cardiotropic properties. Rare causes include bacterial infections. We, herein, describe case ...

Background: Azithromycin maintenance therapy is widely used in cystic fibrosis (CF), but little known about its long-term safety. We investigated whether chronic azithromycin use safe regarding renal function, hepatic cell toxicity and QTc-interval prolongation.Methods: Adult CF patients (72 using for a cumulative period of 364.8 years 19 controls, 108.8 years) from two CF-centers the Netherlan...

Abstract Funding Acknowledgements Type of funding sources: None. Background Due to advances in surgical techniques and immunosuppression survival heart transplant (HT) recipients has improved significantly, with that the prevalence sustained atrial arrhythmias (SAA) these patients is increasing. In HT antiarrhythmic therapy options are limited. Radiofrequency ablation (RFA) represents a viable ...

significance as calcium-channel modulators in the treatment of cardiovascular diseases, such as hypertension, cardiac arrythmias or angina.1 In recent years, interest has also been focused on aza-analogs of dihydropyridines, such as dihydropyrimidines, which show a very similar pharmacological profile to that of dihydropyridine calcium channel modulators.2 In a continuation of these studies, ri...

BACKGROUND Isolated non-compaction of ventricular myocardium (INVM) is characterized by persistent embryonic myocardial morphology without other cardiac anomalies. Congestive heart failure, critical arrhythmias, and systemic thromboemboli are known as major manifestations during childhood. Recently it was reported that there are some patients who seem apparently healthy in adult INVM. Clinical ...

The antipsychotic treatment of schizophrenia is still marked by poor compliance, and drug discontinuation; the development of more effective and safer drugs still remains a challenge. Sertindole is a second-generation antipsychotic with high affinity for dopamine D(2), serotonin 5-HT(2A), 5-HT(2C), and α(1)-adrenergic receptors, and low affinity for other receptors. Sertindole undergoes extensi...

The paper deals with a mathematical model using a structure designed for an application of pattern recognition in ECG signals. The overall process of recognition is consist of generation of a code book, vector quantization, Markov model learning, and recognition. A Hidden Markov Model (HMM) structure with vector–valued observation sequences can be used for the characterization of cardiac arryth...

In 700 patients with acute myocardial infarction admitted to the intensive coronary care unit of our hospital, the incidence and significance of left anterior hemiblock and left axis deviation has been studied in the acute phase of disease. In 102 (14.6%) of the 700 patients, isolated left axis deviation (mean QRS axis-45 degrees) was found and 69 of them (9.9%) met the criteria of left anterio...

Lesions observed in chronic chagasic cardiopathy frequently produce electrocardiographic alterations and affect cardiac function. Through a computerized morphometrical analysis we quantified the areas occupied by cardiac muscle, connective and adipose tissues in the right atrium of dogs experimentally infected with Trypanosoma cruzi. All of the infected dogs showed chronic myocarditis with vari...