Surgical treatment is often accompanied by such complication as bleeding, and ophthalmic surgery not an exception. The bleeding risk depends on many factors, the most significant are age, arterial hypertension, hepatic renal impairment, prior stroke or with oral anticoagulants. aim. To evaluate structure of patients taking novel anticoagulants (NOACs) assessment activated partial thromboplastin...

BACKGROUND In rodents, Growth Hormone (GH) has been shown to stimulate coagulation parameters, including Prothrombin Time (PT), activated Partial Thromboplastin Time (aPTT) and vitamin K dependent coagulation factors. However, there are no reports on the influence of GH replacement therapy on global coagulation tests in Growth Hormone Deficiency (GHD). OBJECTIVE The aim of this study was to i...

Prothrombinase-induced clotting time (PiCT) determines the anticoagulant effects of heparins, low molecular weight heparins (LMWHs), and direct thrombin inhibitors. At present, this is the only method that measures the effects of all of these inhibitors, in contrast to the prothrombin time, activated partial thromboplastin time (aPTT), Heptest, ecarin clotting time, and the chromogenic assays. ...

Abstract This study is aimed at investigating the relationship between treatment modality, glycemic control and blood homeostasis as represented by prothrombin time (PT) activated thromboplastin (APTT) in T2DM patients. Sixty-four type 2 diabetic patients (40 males 24 females) on metformin or insulin both for not less than six months of ages 20 75 years were selected during their visit to Diabe...

This study investigated changes in the coagulation profile of 10 healthy female dogs subjected to ovariohysterectomy. Blood samples were collected three times--before, directly after and 24 h after surgery. Plasma samples were analyzed to determine thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen content, D-dimer content and antithrombin (AT) I...

Background: To determine mean prothrombin time and activated partial thromboplastin time in patients of end stage renal disease having normal baseline coagulation parameters after hemodialysis. Methods: In this cross sectional study 84 patients ,16-70 years of age, with end stage renal disease were selected. Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) were performed p...

Automated procedures involving a chromogenic substrate sensitive to thrombin-sarcosine-Pro-Arg p-nitroanilide were compared with conventional tests for prothrombin times and activated partial thromboplastin times (APTT) and with specific assays for factors V, VII, VIII, IX, X, XI, and XII. The reproducibility and sensitivity of the chromogenic tests were compared with those of the clotting test...

BACKGROUND Bleeding time has been used for a long time as a global test of platelet function. Due to a number of pitfalls the test has been losing popularity. This study was designed to determine the prevalence of prolonged bleeding time in Nigerians with chronic liver disease in relation to other indices of hemostasis. METHODS Bleeding time, platelet count, prothrombin time (PT) and activate...

Impact of gestational diabetes mellitus (GDM) on the coagulation system still remains unclear and there is limited data available regarding haemostatic changes in GDM Bangladesh. This study was aimed at determining plasmaprothrombin time (PT), activated partial thromboplastin (APTT) women with GDM. cross sectional encompassed 44 (age: 28.5±3.8 years, BMI: 27.2±4.0kg/m2; mean±SD) equal number pr...