BACKGROUND AND OBJECTIVES Cryolipolysis is a safe, effective non-surgical procedure to reduce fat. For most cryolipolysis treatments, tissue is pulled between parallel cooling plates with a treatment duration of 60 minutes. A novel contoured cup, medium-sized applicator was developed to increase tissue contact with reduced skin tension and reduced treatment time. This prototype contoured cup wa...

Hyperthermia is one of the modalities for cancer treatment, utilizing the difference of thermal sensitivity between tumor and normal tissue. Interstitial microwave hyperthermia is one of the heating schemes and it is applied to a localized tumor. In the treatments, heating pattern control around antennas are important, especially for the treatment in and around critical organs. This paper intro...

A pilot study on the effect of localised irradiation applied to the site of a standard perforating injury in the rabbit eye, showed that gamma rays limited the formation of post-traumatic vitreoretinal membranes. A controlled study was therefore undertaken to confirm this observation. Twenty-four pairs of rabbits underwent a standard perforating injury in the right eye. One rabbit of each pair ...

Background: Intraoperative radiation therapy (IORT) technique is used to treat a surgically exposed tumor or tumor bed in the treatment of locally advanced intraabdominal, retroperitoneal, pelvic, thoracic, breast and soft tissue tumors. One way to perform IORT is to use an existing linac and modify the treatment head using an applicator system. In this study the objectives were to design, and ...

Three dimensional planning for high-dose-rate (HDR) brachytherapy in cervical cancer has been highly recommended by consensus guidelines such as the American Brachytherapy Society (ABS) and the Groupe Européen de Curiethérapie - European Society for Radiotherapy and Oncology (GEC-ESTRO). In this document, we describe our experience with computed tomography (CT)-based planning using the tandem/r...

I T HAS been recognized that intracavi-tary irradiation is essential in the treatment of carcinoma of the uterine cervix. Since the beginning of the present century3 many applicators have been used to irradiate the uterus and vagina and later several afterloading techniques have been de-scnibed. " 4 Some of the techniques involve the use of remote control5 " and linear distribution of the sourc...

The purpose of this study is to find the uncertainties in the reconstruction of MR compatible ring-tandem intracavitary applicators of high-dose rate image-based brachytherapy treatment planning using rigid registration of 3D MR and CT image fusion. Tandem and ring reconstruction in MR image based brachytherapy planning was done using rigid registration of CT and MR applicator geometries. Verif...

For each patient receiving definitive treatment for cervix cancer, several CT/MR imaging studies need to be registered in order to specify the total physical or biological dose to each fixed tissue voxel in an organ system. This turns out to be a difficult problem due to large localized deformations and displacements of bladder, rectum, vagina, uterus and paracervical tissues due to tumor regre...