Apocrine carcinoma is a very rare form of breast malignancy with an incidence of <1% of female invasive breast carcinoma. We report a case of apocrine carcinoma in a 42-year female with marked adenosis showing apocrine metaplasia and discuss the criteria to diagnose apocrine carcinoma with the emerging concept of androgen receptor positivity with its implication on treatment and management of t...

Hidradenoma papilliferum is a known example of adnexal skin tumours with apocrine differentiation. It is a rare benign tumour which tends to arise from areas with rich concentration of aporine glands such as anogenital region, vulval, perineal, axillae, and periumbilical areas. In this report, the tumour was found in the upper outer quadrant of left breast, being one of the ectopic sites for th...

In order to establish the possible role of androgen in the development of hidradenitis suppurativa the symptomatology of the disease was studied in a group of 70 female patients. The results were compared with those obtained from an age-matched control group of healthy women. The incidence of women with signs of androgenization in the two groups did not differ significantly. The only significan...

A 12-year-old domestic short-haired cat was referred for evaluation of periocular masses. The tail had similar masses and was amputated previously by the referring veterinarian. On examination, multiple pigmented nodules, 3-15 mm in diameter, were found in the periocular skin, primarily involving the palpebral eyelid margin. A wedge excisional biopsy revealed small cuboidal cells forming multip...

BACKGROUND Apocrine mixed tumor is usually found in parotid glands. Its cutaneous counterpart is rare and its occurrence in the eyelids is even rarer. CASE PRESENTATION This study reports an apocrine mixed tumor of the upper left eyelid in a 68 year-old lady with a history of breast cancer. This mass appeared about 3 years ago, as a slowly growing small nodule, and was completely excised. On ...

Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on effectiveness of different methods, there no single therapeutic approach treatment patients with EMPD and their subsequent management. The use surgical laser therapy local cytotoxic drugs has number limitations. advantages using photodynamic (PDT) in ar...

Cell secretion is an important physiological process that ensures smooth metabolic activities and tissue repair as well as growth and immunological functions in the body. Apocrine secretion occurs when the secretory process is accomplished with a partial loss of cell cytoplasm. The secretory materials are contained within secretory vesicles and are released during secretion as cytoplasmic fragm...

Sir, Fox-Fordyce disease (FFD) occurs as a chronic, itchy, papular skin eruption principally located in the apocrine gland-bearing areas (1, 2). Although it usually appears in a symmetrical distribution on the axillae and pubic area, it can also occasionally a¡ect the labia, perineum, mammary areolae, presternal area, umbilicus and the medial aspect of the upper thighs. Hair growth in the a¡ect...