A 60-year-old woman, free of other disease, with severe clinical hyperthyroidism had normal total serum T4 with elevated free T4 concentration and T3 resin uptake characteristic of hyperthyroidism, with thyroid binding globulin (TBG) deficiency. However, serum TBG concentration as determined by immunoassay was normal, suggesting that the biochemical defect affecting the T4 binding sites did not...

Abnormalities in thyroid function are associated with many psychiatric symptoms. We present a report of a 15-year-old girl who was admitted to the psychiatry inpatient unit with symptoms of suicidal behavior, irritability, and impulsivity. One year previously, she had become more short-tempered, and had started to cut her wrists impulsively. Laboratory tests revealed subclinical hyperthyroidism...

Hyperthyroidism is a relatively prevalent condition, and is one of the most common endocrine problems seen in clinical practice, high serum cholesterol and increased oxidative stress are common associated risk factors of hyperthyroidism. Multivitamin deficiencies in folate and vitamin C are also one of the hyperthyroidism complications. Individually or combined Folic acid and vitamin C were int...

Although gynaecomastia is a well-documented manifestation among male patients with hyperthyroidism, it is extremely rare to present as the initial or chief complaint in a subject with undiagnosed hyperthyroidism. We report a case of a 38-year-old Chinese man presenting with painful enlargement of both breasts of one month's duration. Examination revealed bilateral tender gynaecomastia. In addit...

Acute myocardial ischemia is a rare and possibly life-threatening manifestation of hyperthyroidism. We describe a 48-year-old woman with severe coronary vasospasm associated with hyperthyroidism. The patient presented with chest pain and increasing shortness of breath for several days. Acute non-ST elevation myocardial infarction was diagnosed. Coronary angiography revealed diffuse vasoconstric...

Seven patients suffering from hyperthyroidism have been carefully studied. An analysis of their experimental data provides definite evidence in favour of an associated hyperparathyroidism being the direct cause of the excessive mobilization and excretion of calcium and phosphorus. Two patients suffering from hyperthyroidism with an associated hypoparathyroidism were studied. Both patients were ...

the influence of hypo- and hyper-thyroidism on spermatogenesis was studied in 60-day-old adult malewistar rats. to confirm hypo- and hyper-thyroidism, the concentration of plasma thyroid hormones wereassayed by radioimmunoassay. the hypothyroid state, induced by administration of 25 mg/kg/daymethimazole for 5 successive days, resulted in significant decrease in the number of sertoli cells, sper...