complex: the low intrinsic protease activity of the pro-caspase is then sufficient to trigger intermolecular cleav-age and subsequent activation. Formation of such pro-44 Lincoln's Inn Fields London WC2A 3PX caspase complexes is mediated by the prodomains of the apical caspases that interact with adaptor molecules United Kingdom to form the " apoptosome. " The adaptor molecules serve as protein...

Arsenic is a very dangerous metal that widely distributed in the environment as result of anthropogenic and natural processes. On other hand, it thought treatment with flavonoids may protect against arsenic toxicity. Carvacrol (CRV) naturally occurring phenolic compound anti-inflammatory, anti-apoptotic, antioxidant properties. This study aims to investigate protective effects CRV on sodium ars...

The aim of the study was to develop a reliable and cost-effective method for detection nonsense mutation in APAF1 gene causing lethal effect called HH1 (Holstein Haplotype1) evaluate its prevalence sample Polish Holstein-Friesian bulls. One hundred seventy eight bulls born between 1996 2017 were included analysis. They kept four artificial insemination centers have pedigree known carrier HH1. A...