In human beings, susceptibility to anxiety disorders can be relatively high during adolescence. Understanding the ontogeny of anxiety-like behavior in laboratory rodents has implications for developing anxiolytic drugs that are suitable for this age group. Given the dearth of information about adolescent rodents, this study examined the response of both male and female adolescent, late adolesce...

Atopic dermatitis (AD) is a chronic, recurrent, itchy eczematous disorder associated with impaired skin barrier functions. The coexistence of anxiety, depression, and social withdrawal problematic in AD. At present, psychological factors such as stigma resulting from appearance insomnia pruritus are possible causes, but the detailed causes depression anxiety AD unknown. Here we hypothesized tha...

Benzodiazepine receptor agonists are widely prescribed therapeutic agents that alter gamma-aminobutyric acid (GABA)A activity and have anxiolytic effects. Post-operative use of benzodiazepines is a risk factor delirium. Inflammatory conditions the effects benzodiazepine. We investigated effect diazepam, typical benzodiazepine anxiolytic, on changes in emotional behavior mice hole-board test aft...