BACKGROUND Information is scarce on the impact of the clinical electronic record on the frequency and severity of medication errors in acute geriatric patients. MATERIAL AND METHODS An analytical and descriptive pre-post study was conducted on the implementation of computerized provider order entry systems (CPOE), over a 6 year period. A voluntary reporting system was used to detect the medic...

The waste of multiple residually harmful hospital pharmaceutical materials such as antibiotics, chemicals, hormonal waste, and residual particles from different types medicine used in anticonvulsants antipyretics is one the most serious health issues confronting workers today. During past decades, many efforts were made to remove effects this environmental pollution. Efficient, stable, fast, en...

Based on observations that fever is suppressed under several physiological circumstances the existence of endogenous antipyretically active molecules has been postulated. A large number of experimental and some clinical studies provided evidence that the neuropeptides arginine vasopressin (AVP), αand γ-melanocyte stimulating hormones (α-MSH, γ-MSH) and adrenocorticotropic hormone (ACTH) as well...

OBJECTIVE To compare the efficacy and safety of nimesulide and paracetamol as antipyretic agents. DESIGN Double blind, randomized clinical trial. METHODS Hospitalized patients having fever due to a variety of infections were given either drug in a randomized manner. (Nimesulide group = 49, Paracetamol group = 50). Serial axillary temperature was recorded after drug administration and side e...

PURPOSE Low-dose naltrexone (LDN) is used in a wide range of conditions, including chronic pain and fibromyalgia. Because of the opioid antagonism of naltrexone, LDN users are probably often warned against concomitant use with opioids. In this study, based on data from the Norwegian prescription database, we examine changes in opioid consumption after starting LDN therapy. METHODS We included...

OBJECTIVES The aim of the study was to evaluate the effects of infant formula supplemented with 2 human milk oligosaccharides (HMOs) on infant growth, tolerance, and morbidity. METHODS Healthy infants, 0 to 14 days old, were randomized to an intact-protein, cow's milk-based infant formula (control, n = 87) or the same formula with 1.0 g/L 2'fucosyllactose (2'FL) and 0.5 g/L lacto-N-neotetraos...