نتایج جستجو برای: antioxidant potential aop
تعداد نتایج: 1145933 فیلتر نتایج به سال:
Efforts are underway to transform regulatory toxicology and chemical safety assessment from a largely empirical science based on direct observation of apical toxicity outcomes in whole organism toxicity tests to a predictive one in which outcomes and risk are inferred from accumulated mechanistic understanding. The adverse outcome pathway (AOP) framework provides a systematic approach for organ...
BACKGROUND The introduction of whole new foods in a population may lead to sensitization and food allergy. This constitutes a potential public health problem and a challenge to risk assessors and managers as the existing understanding of the pathophysiological processes and the currently available biological tools for prediction of the risk for food allergy development and the severity of the r...
This document is an overview of formal models for AOP. It covers most existing formalisms. Instead of explaining the technical details of each work, we identify key concepts for AOP, and mention how they are modeled.
Objective COMT rs4680 (Val158Met) genotype moderates the effect of cannabis on the age of onset of psychosis (AoP). We investigated the association between rs4680 and AoP, after adjusting for relevant covariates, in a Canadian Caucasian sample. Methods One hundred and sixty-nine subjects with psychosis were recruited. AoP, defined as age of DSM-IV diagnosis was established using the Structure...
AOP [1] has been proposed as a way to write programs that elegantly implement crosscutting concerns. This paper presents initial results of an exploration into whether this is true for AspectJ [2]. During this this exploration we have written several small and medium scale systems using AspectJ. Writing elegant code requires good implementation structure. This paper presents some of the more in...
Apnea of prematurity (AOP) is considered a risk factor for neurodevelopmental disorders in children based on epidemiological studies. This idea is supported by studies in newborn rodents in which exposure to intermittent hypoxia (IH) as a model of AOP significantly impairs development. However, the severe IH used in these studies may not fully reflect the broad spectrum of AOP severity. Conside...
Aspect oriented programming AOP controls tangling of concerns by isolating aspects that cross cut each other into building blocks Component based programming CBP supports software development by isolating reusable building blocks that can be assembled and connected in many di erent ways We show how AOP and CBP can be integrated by introducing a new component construct for programming class coll...
Aspect-oriented programming (AOP) is an emerging technique that provides a mechanism to clearly encapsulate and implement concerns that crosscut other modules. It is claimed that this technique improves code modularization and therefore reduces complexity of object-oriented programs (OOP). Most of the proposed complexity measurement frameworks for AOP are for AspectJ programming language. In th...
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