OBJECTIVE The emergence of multiresistant microorganisms has been a concerning matter worldwide in the last decades. Indiscriminate use of antibiotics has been associated to this phenomenon. The present study was designed to determine the pattern of antimicrobial drug use in an urban community. METHODS A population-based cross-sectional study was carried out and 6,145 subjects of all ages liv...

Translocation of cell-penetrating peptides is often promoted by increased content of arginine or other guanidinium groups. However, relatively little research has considered the role of these functional groups on antimicrobial peptide activity. This study compared the activity of three histone-derived antimicrobial peptides-buforin II, DesHDAP1, and parasin-with variants that contain only lysin...

INTRODUCTION Point prevalence surveys have been used internationally to characterize the use of antimicrobial agents. The primary objective of this study was to determine prevalence of antimicrobial use in the oncology population in Qatar. METHODOLOGY Data was collected from the National Center for Cancer Care and Research hospital over 3 separate days during a two week period. Adults admitte...

Can the use of serum procalcitonin levels safely reduce antimicrobial use in intensive care unit (ICU) patients? We performed a systematic literature review that identified 6 published randomized controlled trials comparing PCT-guided antimicrobial therapy to usual care in ICU patients, extracting data on ICU and patient characteristics, PCT guideline content, intensity of antimicrobial exposur...

background: anti-microbial agents have been used as a chemotherapeutic agent to improve oral health. this in vitro study was carried out to determine antimicrobial efficacy of different toothpastes and mouthrinses against the oral pathogens.     methods: a total of five toothpastes and five mouthrinses were tested for their antimicrobial activity against three oral pathogens namely, streptococc...

lactobacillus spp are a group of gram-positive, non-spore forming, cocci or rod shaped, catalase negative organisms that benefit to the host. prebiotics are non-digestible food ingredients that stimulate the growth and /or activity of bacteria in the digestive system in ways claimed to be beneficial to health. this study was conducted in order to investigate the effects of selected probiotic mi...

in the present study, the antimicrobial tests of patchouli oil were studied by using molecular docking technology and antimicrobial test in vitro. five biological macromolecule enzymes, required by the bacteria in the process of biosynthesis were selected as target molecules. five antibiotics benzylpenicillin, sulfadiazine, trimethoprim, rifampicin and ciprofloxacin, which are generally acknowle...

introduction: zhumeria majdae is an herbal plant which is only found in hormozgan province. the aim of this study was to compare the antimicrobial property and toxicity of essential oil (eo) and encapsulated form of the essential oil (efeo) of zhumeria majdae. materials and methods: first, the plant was dried, grinded, and its eo extracted by hydrodistallation. then, the eo was encapsulated by ...

results the mean of the inhibition zone diameter around the discs of green tea extract in all concentrations was significantly less than 1% sodium hypochlorite (p < 0.001). the antimicrobial effect increased in higher concentrations of extracts of green tea (p < 0.001). conclusions although the antimicrobial effect increases in higher concentrations of extracts of green tea, 1% sodium hypochlor...

hyssopus of­ficinalis l. is one of the most important medicinal plants. medicinal herbs are contaminated by microorganisms. conventional methods for reducing of microbial loads such as ethylene oxide, propylene oxide and also use of steam are hazardous and instead, non-thermal process such as microwave and gamma radiation are being used widely in order to eliminate the microbial contaminations ...