BACKGROUND The aim of this in vitrostudy was to examine and compare the effect of photodynamic therapy and solution containing nano particles Ag/ZnO on adhesion of endodontic sealers to dentinal walls of human root canal. MATERIAL AND METHODS Ninty single-rooted human teeth were selected and their clinical crown was cut from the cemento-enamel junction zone. Canals were prepared by RaCe rotar...

Candida albicans is one of the most common causative opportunistic infections. Treatment candidiasis challenging considering few antifungal drugs available and increase in resistance. Antimicrobial photodynamic therapy (aPDT) a recently developed therapeutic option that combines non-toxic photosensitizer (PS) light to kill microbial pathogens. Targeting virulence, defined as ability pathogen ca...

Skin mycoses are caused mainly by dermatophytes, which are fungal species that primarily infect areas rich in keratin such as hair, nails, and skin. Significantly, there are increasing rates of antimicrobial resistance among dermatophytes, especially for Trichophyton rubrum, the most frequent etiologic agent worldwide. Hence, investigators have been developing new therapeutic approaches, includ...

objective(s)   although photodynamic therapy is considered as a noninvasive method, most photosensitizers are susceptible to  ultrasound.  therefore,  it  is  expected  that  the  combination of  two  activation  methods  might  have  a synergistic effect. this probable effect has been investigated in this study.   materials and methods   this  study  was  conducted  on  colon  carcinoma  tumor...

photodynamic therapy (pdt) using 5-aminolevulinic acid (5-ala)-induced protoporphyrin ix (ppix) has been considered as a new method for treating neoplasms. however, ala-pdt is suboptimal for thick tumors. searching for new approaches, we investigated the effect of adding differentiation therapy (dt) with vitamin e succinate (ves) to pdt in human prostate ln-cap-fgc10 cancer cells in vitro . the...

OBJECTIVE This study investigated in vitro the photodynamic antimicrobial effects of the photosensitizer malachite green on clinical strains of Staphylococcus, Enterobacteriaceae, and Candida. MATERIALS AND METHODS Thirty-six microbial strains isolated from the oral cavity of patients undergoing prolonged antibiotic therapy, including 12 Staphylococcus, 12 Enterobacteriaceae, and 12 Candida s...

conservation of deciduous teeth with pulp alterations caused by caries or trauma is a major therapeutic challenge in pediatric dentistry. it is essential that the sanitizers used in root canal procedures perform well in eliminating bacteria. antimicrobial photodynamic therapy (pdt) is an emerging and promising adjuvant therapy for endodontic treatment in an attempt to eliminate microorganisms p...

Multifunctional nanoplatforms based onmesoporous silica nanoparticles (MSNs) have recently shown great promise in drug delivery and therapy. Herein, a multifunctional nanoplatform based on MSNs is fabricated by a modified micro-emulsion method for drug delivery and imaging-guided chemo/photodynamic synergistic therapy. Carbon dots (C-dots) and a photosensitizer, rose bengal (RB), are embedded i...