نتایج جستجو برای: antimalaria activities
تعداد نتایج: 377407 فیلتر نتایج به سال:
Sintrong (Crassocephalum crepidioides) merupakan kelompok tanaman dengan batang lunak yang dipercaya bisa mengobati berbagai macam penyakit, seperti gangguan pencernaan, sakit kepala, perut, luka, antelmetik, antiinflamasi, antidiabetes, dan antimalaria. Daun sintrong mengandung senyawa metabolit sekunder yaitu flavonoid diketahui memiliki aktivitas sebagai antiinflamasi. Penelitian ini bertuju...
Penelitian di bidang farmasi terbantu dengan berkembangnya teknologi dan sains, salah satunya kimia medisinal yang berkaitan penemuan obat maupun desain pengembangan pengobatan. Komputasi merupakan satu teknik dalam metode molecular docking Hubungan Kuantitatif Struktur Aktivitas (HKSA) meliputi sintesis, purifikasi, desain, identifikasi serta uji aktivitas dari suatu senyawa. Metode digunakan ...
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium falciparum by antibody repertoire cloning from phage display libraries generated from immune Gambian adults. Although these novel reagents bind with strong affinity to malaria parasites, it remains uncl...
At the end of the 19th century, after having long neglected sanitary conditions in rural areas, Argentinean public health authorities began to recognize the need to combat malaria in the country's northern provinces. The disease was proliferating among workers in the sugarcane and cotton industries, jeopardizing national and international economic interests. The crusade against malaria involved...
Anopheles gambiae is a primary vector of Plasmodium falciparum, a human malaria parasite that causes over a million deaths each year in sub-Saharan Africa. Population genetic tests have been employed to detect natural selection at suspected A. gambiae antimalaria genes, but these tests have generally been compromised by the lack of demographically correct null models. Here, we used a coalescent...
Plasmodium falciparum is a global problem resulting in considerable morbidity and mortality [1,2]. Plasmodium vivax also causes appreciable morbidity and has become chloroquine – resistant in some endemic areas [3,4]. Therefore, the accurate diagnosis of malaria in febrile patients is essential for optimal patient management and the rational use of antimalaria drugs in malaria control programs....
Hydroxychloroquine (HXQ) sulphate is a synthetic antimalaria drug that is widely used in rheumatology due to its immunosuppressive properties. Delayed-type sensitization to this drug is rare. A 47-year-old woman diagnosed with HLA B27 ankylosing spondylitis was treated with HXQ for 22 days and had to discontinue the drug due to gastric intolerance. Five days later the patient developed erythema...
Diabetes melitus merupakan penyakit kronis gangguan metabolisme yang ditandai dengan hiperglikemia dan karbohidrat, dimana kurangnya sekresi insulin berjumlah 90-95% terdiagnosis tipe dialami oleh sebagian besar penderita diabetes melitus. Strategi dalam menangani antidiabetes adalah mencari senyawa baru pada tumbuhan obat. Tumbuhan cep-cepan (Castanopsis costata) famili Fagaceae sering digunak...
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