This paper presents a geomorphological map of the Hérens valley in the Western Swiss Alps. With an area of 270 km and altitudes ranging from 470 to 4357 m a.s.l., this valley is one of the main secondary catchments of the Upper Rhône valley. The high differences in altitudes, combined with a varied geology, create an important geomorphic diversity. The main processes active in mountain areas, t...

As troves of microbiome sequencing data provide improved resolution of patterns of microbial diversity, new approaches are needed to understand what controls these patterns. Many microbial ecologists are using cultivated model microbial communities to address this challenge. These systems provide opportunities to identify drivers of microbiome assembly, but key challenges and limitations need t...

In the construction of large antibody libraries by in vivo recombination, two non-homogeneous loxP sites are required for the exchange of V genes between phagemids to create many new VH-VL combinations. The mutated loxP511 was designed not to recombine with the wild-type loxP (loxPwt) in early studies and a combination of the two has been used to construct antibody libraries. But recent reports...

Contents 1. Introduction – biodiversity in agricultural ecosystems 2. Planned diversity and the functioning of agricultural systems 2.1. Intraspecific diversity 2.2. Species diversity 2.3. Habitat and landscape diversity 3. Unplanned diversity and the functioning of agricultural systems. 3.1. Pollination services 3.2. Soil processes 3.3. Natural pest control 4. Conclusions Bibliography Biograph...

The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the UK and the USA were sequenced at the cps locus to elucidate serologically mistyped or non-typable isolates. We identified a novel serotype 33B...

The evolution of multicellularity was one of the key innovations in the history of life on Earth. Virtually all morphological and ecological diversity in macro-organisms builds upon the evolutionary potential associated with multicellularity. We examined the potential for ecological diversity to rapidly arise following transitions to multicellularity. Replicate microcosms containing the yeast S...

Approximately 7000 marine zooplanktonic species have been described so far for the World Ocean; in the South Atlantic the presence of 40% of these has been confirmed, and an additional 20–30% are expected to be recorded in the future. The overall number of described species is very low when compared with other communities, and yet it may not be too far from the final, complete inventory. Very a...

Punctuated antigenic change is believed to be a key element in the evolution of influenza A; clusters of antigenically similar strains predominate worldwide for several years until an antigenically distant mutant emerges and instigates a selective sweep. It is thought that a region of East-Southeast Asia with year-round transmission acts as a source of antigenic diversity for influenza A and se...

The identification of mutations that enhance antibody affinity while maintaining high antibody specificity and stability is a time-consuming and laborious process. Here, we report an efficient methodology for systematically and rapidly enhancing the affinity of antibody variable domains while maximizing specificity and stability using novel synthetic antibody libraries. Our approach first uses ...