In the title compound, C(14)H(20)N(2)O(2)S, the sulfonamide O atoms lie to one side of the benzene ring and the amino-bicyclo-hepta-nyl to the other side [C(ar)-S-N-C torsion angle = -57.93 (11)°; ar = aromatic]. An intra-molecular N-H⋯N hydrogen bond is formed. In the crystal, a supra-molecular chain is formed along the b axis via N-H⋯O and N-H⋯N hydrogen bonds.

To assess the presence and distribution of the sul genes (sul1, sul2, and sul3) and plasmids in human-mediated environments of north Vietnam, we examined a total of 127 sulfonamide-resistant (SR) bacterial isolates from four shrimp ponds (HNAQs), a city canal (HNCs) and three fish ponds that received wastewater directly from swine farms (HNPs). Results from the SR isolates revealed that sul gen...

deaths continue in their present ratio to be, as they are, the reproach of our art. Attempts more or less successful to prevent them by means of antiseptics are not new. Already the literature on antiseptics in midwifery, although not so bulky as in surgery, is yet by no means inconsiderable. Antiseptics and disinfectants have long been employed in obstetric practice; but of recent years, since...

Factors other than antimicrobial activity of soaps and antiseptic agents used for hand hygiene by health personnel play a role in compliance with recommendations. Hand hygiene products differ considerably in acceptance by hospital personnel. If switching from a nonmedicated soap to an antiseptic agent or increased use of an existing antiseptic agent for hand hygiene prevented a few more infecti...

Joseph S. Solomkin, John E. Mazuski, Ellen J. Baron, Robert G. Sawyer, Avery B. Nathens, Joseph T. DiPiro, Timothy Buchman, E. Patchen Dellinger, John Jernigan, Sherwood Gorbach, Anthony W. Chow, and John Bartlett Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Surgery, Washington University School of Medicine, St. Louis, Missouri; Department...

An attempt has been made to study the action of antiseptics on artificial streptococcal ;wounds' in mice by a published technique (Martin, 1959). The results were not in agreement with those of Martin and the possible reasons for this are discussed. Suggestions are made for modifying the original method to increase its scope and precision. The production and treatment of Ps. pyocyanea and Kl. a...

„ Increasing bacterial resistance to antibiotics makes the management of superficial skin infections a major medical challenge. Antiseptics have broader spectrums of antimicrobial activity and a reduced potential for selection of bacterial resistance, relative to antibiotics. Consequently, antiseptics are appropriate alternatives to antibiotics for the prevention and treatment of superficial sk...

We present here the draft genome sequence of the first New Delhi metallo-β-lactamase (NDM-1)-producing Escherichia coli strain, belonging to sequence type 155 (ST155), isolated in Peru. Assembly of this draft genome resulted in 5,061,184 bp, revealing a clinically significant resistome for β-lactams, aminoglycosides, tetracyclines, phenicols, sulfonamides, trimethoprim, and fluoroquinolones.

M. Vermeuil, in a communication on " Erysipelas and the Antiseptic Method," directs attention to the fact that in the practice of surgery, where the antiseptic method is adopted, erysipelas, if it has not completely disappeared, has become extremely rare, has almost ceased to be epidemic and even endemic, being only worthy of the term sporadic. The observations, of which he gives an analysis, l...

Royal Infirmary. A saturated solution of camphor in strong carbolic acid has long been known; but has attracted little notice as a therapeutic agent. Dr. Cochran,* of Shomond, Wis., has recommended its use, both locally and internally, as an antiseptic agent. He gives it internally in ten-drop doses in capsule, and injects it hypodermically; he also employs it externally. The camphor is dissolv...