Background and purpose: In most cases, drugs used for chemotherapy are ineffective and have unpleasant side-effects. This has made scientists to find more effective drugs with less toxicity. Lagenaria siceraria is an important medicinal plant in the world and anti-tumoral activity of Lagenaria species has been reported in some studies. This study was designed to evaluate the anti-tumoral effect...

Probiotics are alive microorganisms which have useful effects on health of host by balancing its intestinal micro flora. Nowadays, probiotics are known as a factor for prevention of infectious diseases and cancer. Anti cancer properties of probiotics exert with the detoxification of materials that cause genetic damages. The present study aimed to systematically review on studies in checking pos...

Background and purpose: Gastric cancer is the third most common cancer in Iran and the second leading cause cancer-related death worldwide. Shark cartilage prevents angiogenesis in vivo and in vitro, however, its role on angiogenesis or anti-tumor responses in human is not clear yet. We studied the effects of oral treatment of shark cartilage on peripheral Treg frequency and TGF-β as suppressor...

Background and purpose: Adenocarcinoma gastric cancer is one of the most common cancers of upper gastrointestinal tract. Many natural compounds are known to have anti-tumor activities through induction of tumor cell apoptosis. Tribulus terrestris is a plant with antioxidant and anti-inflammatory effects that has been recommended in the world and Iranian traditional medicine. These effects have ...

Background: The use of medicinal herbs in traditional medicine has been important and many of these plants have antioxidant, anti-inflammatory, antimicrobial and anti-cancer effects. Objective: The aim of this study was to evaluate the antibacterial and anti-cancer effects of Artemisia turcomanica extract on gastric cancer cell line (AGS) and its effect on expression of cyclin D1 and cyclin E g...