Objetivo: verificar associação do declínio cognitivo e dos fatores socioeconômicos com o risco cardiovascular em idosos Alzheimer. Método: estudo transversal, que se incluíram 75 Verificaram-se pressão de pulso, cardiovascular, Miniexame Estado Mental, Miniavaliação Nutricional exames bioquímicos. Resultados: 92% pacientes apresentaram cognitivo, média três anos escolaridade. Houve prevalência ...

Statin treatment has been associated with a reduced risk of Alzheimer disease and decreased amyloid deposition in mouse models. No animal studies have reported effects of statins on tau aggregates and neurofibrillary tangles (NFTs), the pathological hallmarks of Alzheimer disease that correlate with dementia. We investigated the effect of statins on NFTs in a transgenic mouse tauopathy model an...

Abstract COVID-19 is a new disease that has become pandemic. This should be watched out for because transmission relatively fast, mortality rate cannot ignored, and there no definitive therapy. After COVID 19, people will more selective in the food they eat. The types of chosen were those have health benefits, especially as immunity boosters. problem was what products can provide these benefits...

Within primary progressive aphasia the logopenic variant remains less understood than the two other main variants, namely semantic and non-fluent progressive aphasia. This may be because of the relatively small number of explored patients and because of the lack of investigations with a comprehensive three-level characterization of cognitive, brain localization and biological aspects. The aim o...

Many of the molecular and pathological features associated with human Alzheimer disease (AD) are mirrored in the naturally occurring age-associated neuropathology in the canine species. In aged dogs with declining learned behavior and memory the severity of cognitive dysfunction parallels the progressive build up and location of Aβ in the brain. The main aim of this work was to study the biolog...

OBJECTIVE To review the drugs commercially available at present and in the near future in relation to the evolution of Alzheimer disease, bearing in mind the possible psychiatric disorders which may be associated with the disease. DEVELOPMENT The therapeutic approach is planned according to the different phases of the disease. In the preclinical phase, anti-inflammatory drugs and estrogens in...

We don’t understand Alzheimer, its origin and disease mechanisms. The absence of disease-modifying treatments for Alzheimer today is due to the amyloid hypothesis, a misguided hypothesis of Alzheimer’s etiology, which has dominated research, drug development, clinical trials 30 years. However, the hypothesis is not dead yet, as exemplified by the recent resurrection of clinical with aducanumab....

Endocannabinoid (ECB) system plays a vital role in responses to stress. Moreover, ECB and its receptors cause anti-inflammatory, anti-oxidative and neuroprotective effects by modulating neuronal, glial and endothelial cell functions. A number of studies have demonstrated ECB system notably defects in neurotraumatic and neurodegenerative diseases like epilepsy, TBI, Alzheimer’s disease and...

Implication for health policy makers/practice/research/medical education: This article aims to introduce saffron as a useful herbal medicine. Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences; Published by DOCS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution...