PURPOSE: To report an unusual case of fulminant anterior uveitis, confirmed as endogenous Listeria monocytogenes infection. SUBJECT: A 67-year-old man with multiple comorbidities acutely developed a severe endogenous anterior uveitis. RESULTS: L. monocytogenes, a ubiquitous Gram-positive bacillus, was directly indicated by culture and PCR. Early and aggressive treatment with intravenous antibio...

PURPOSE To measure thrombopoietin (TPO) levels in the serum and aqueous humors of patients with noninfectious acute anterior uveitis. METHODS A prospective, comparative, controlled study. Serum and aqueous humors were obtained from the eyes of 16 patients with noninfectious acute anterior uveitis. TPO levels were measured using an enzyme-linked immunosorbent assay (ELISA). The results obtaine...

PURPOSE To determine the aetiology and clinical characteristics of patients with uveitis in a tertiary ophthalmology centre in northern Thailand. METHODS Standard ophthalmological examination and laboratory screening blood tests were performed in 200 consecutive new patients with uveitis. Patients were classified according to the location and aetiology of the uveitis. Specific clinical charac...

Cataract formation is an especially common complication resulting from uveitis. It is rare in posterior uveitis, but occurs in up to 50% of patients with anterior and intermediate uveitis (21), and in nearly 80% of patients with Fuchs heterochromic iridocyclitis (FHC). Duration and intensity of inflammation, and treatment, e.g. corticosteroids and previous vitrectomy, are critical determinants ...

PURPOSE To present a series of microsporidial keratoconjunctivitis in 24 eyes. METHODS Retrospective non-comparative observational case series. Medical records were retrieved and individuals evaluated based on symptoms, risk factors, visual acuity, slit lamp biomicroscopy and pathological examination of cornea epithelial scrapings. Demographic features, clinical course, predisposing factors, ...

Aim To determine the risk factors for macular edema (ME) in children with uveitis. Methods A retrospective study was conducted of 150 pediatric patients (264 eyes) uveitis attending 2 tertiary medical centers. Data were collected from files on demographics, type uveitis, etiology, clinical findings, treatment, and time to development ME. Risk ME identified. Results developed 63 eyes (23.9%) ove...

AIM To assess the prevalence of active and inactive uveitis unrelated to previous surgery or trauma in an urban population in southern India. METHODS As part of the Andhra Pradesh Eye Disease Study, 2522 subjects (85.4% of those eligible), a sample representative of the population of Hyderabad city in southern India, underwent interview and detailed dilated eye examination. Presence of sequel...

During the first 5 years (1963-67) of a new Medical Ophthalmology Unit, 204 of the 1700 admissions had endogenous uveitis. It was anterior in 141 (70 Y.), posterior in thirty-three (16%) and generalized in thirty (14%). Acute uveitis in ninety-seven patients ended in the course of months whereas chronic uveitis in 107 was measured over the years, punctuated by relapses. Sex distribution was equ...

PURPOSE To determine in rabbits whether periocular injection of ketorolac tromethamine effectively delivers the drug to the eye and, if so, whether this is efficacious in the treatment of experimental uveitis. METHODS Ketorolac was administered by anterior subconjunctival injection, posterior periocular injection, intramuscular injection, or topical eye drops. The aqueous and vitreous were as...

Uveitis is considered a rare complication of leptospirosis. This report describes an epidemic of uveitis among patients with leptospirosis and provides data, using polymerase chain reaction (PCR) amplification of Leptospira DNA, that the pathogenesis is associated with anterior chamber spirochetes. Forty-six uveitis patients, 49 uveitis controls, and 54 cataract controls were enrolled at Aravin...