Annexin II has been identified as a human cytomegalovirus (HCMV)-binding protein, shown to be a component of purified virions and proposed as a cellular receptor for the virus. In addition, annexin II is capable of associating with the major HCMV envelope glycoprotein, gB (gpUL55). As one approach to examine the role of annexin II in virus entry, a high-titre polyclonal annexin II-specific anti...

Pure, highly crystalline AIPO,-H2 is synthesized from an aluminophosphate gel containing dipentylamine and characterized using X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscopy, thermogravimetry and solid-state nuclear magnetic reson!nce spectroscopy. The AIPO,-H2 structure has orthorhombic symmetry with cell parameters of a = 16.184(5) A, b = 9.914(3) A a...

The effect of side chain conjugation on 7-dehydroxylation of bile acids has been investigated. C24-bile acids and their glycine and taurine conjugates and keto bile acids were incubated with pure strains of Eubacterium sp. VPI 12708. Bile acids of the 5 alpha- or 5 beta-series with a free terminal carboxyl group and a 3 alpha, 7 alpha-dihydroxy system were very effectively 7 alpha-dehydroxylate...

It has been widely accepted that microparticles expose phosphatidylserine which in turn binds annexin V. It was the objective of this study to compare the antigenic characteristics and phospholipid-dependent procoagulant activity of annexin V positive and -negative subpopulations of platelet-derived microparticles. Annexin V positive and -negative microparticles were identified and characterise...

PURPOSE Annexin A2 has been shown to play a role in many neovascularization diseases. We investigated the effect of vascular endothelial growth factor (VEGF) on annexin A2 expression and related intracellular signaling mechanisms in a mouse model of ischemia-induced retinal neovascularization. METHODS Annexin A2 expression and the effect of vascular endothelial growth factor (VEGF) on annexin...

AIM To investigate the expression of annexin II in gastric carcinoma and its role in the metastasis of gastric cancer. METHODS The expression of annexin II in 51 cases of gastric carcinoma and 24 cases of adjacent tissues was detected by immunohistochemistry. The relationship between annexin II and clinical features of gastric cancer was analyzed. Annexin II specific siRNA was used to inhibit...

This study examined the impact of palatal lift intervention on articulatory kinematics for a speaker with acquired velopharyngeal incompetence (VPI) following brainstem tumor excision. Articulatory adaptations to VPI management may be expected in response to sudden changes in vocal tract adrodynamics and acoustics. This investigation was designed to address the following research qtlestions: (1...

Objective: Velopharyngeal insufficiency is usually defined as failure of the velopharyngeal sphincter (mainly: velum, lateral and posterior pharyngeal walls) to separate the oropharynx from the nasopharyngeal space during speech and deglutition resulting in swallowing and speech difficulties with adverse effects on communication skills and the psychological status of the patient. Methods: We pr...

The distribution and regulation of annexin A5 expression, a gonadotropin releasing hormone (GnRH) receptor regulated protein in gonadotropes and luteal cells, in the testes of rats were examined. Immunocytochemical staining revealed high levels of annexin A5 in the Leydig and endothelial cells and lower levels in the primary spermatocytes and sperm. Hemicastration significantly increased the an...

BACKGROUND There is evidence that circulating microparticles (MPs) and annexin (+) platelet-derived MPs (PDMPs) are increased in inflammatory bowel disease (IBD). The aim of our study was to characterize the abundance, origin, and annexin V binding of MPs in patients with IBD and correlate them with the disease characteristics. METHODS Case-control study of 46 IBD patients (23 Crohn's disease...