CONTEXT Restenosis within bare-metal stents is often treated with repeat percutaneous coronary intervention, although subsequent recurrence rates are high, with vascular brachytherapy (VBT) affording the best results. The effectiveness of drug-eluting stents in this setting has not been established. OBJECTIVE To investigate the safety and efficacy of the polymer-based, slow-release paclitaxel...

Coronary artery disease remains a major health problem throughout the world. Since the inception of percutaneous transluminal coronary angioplasty in 1978 and the addition of stents in the early 1990s, much progress has been made in the treatment of atherosclerotic obstructive coronary artery disease. Percutaneous coronary intervention (PCI) has eclipsed coronary artery bypass grafting surgery ...

Background: This study assessed the application value of 64-slice spiral computed tomography angiography (CTA) in a follow-up evaluation of patients receiving coronary stent implantation. Materials and Methods: A total of 468 patients who underwent percutaneous coronary intervention (PCI) at our hospital between January 2013 and October 2016 were selected for this study. Coronary angiography an...

OBJECTIVES We examined the relative contributions of inflammation and arterial injury to neointimal formation in a porcine coronary overstretch restenosis model. BACKGROUND Previous studies established that stents cause neointimal proliferation proportional to injury. Although inflammation has been postulated to be a major contributor to restenosis after angioplasty, there is a paucity of dat...

OBJECTIVE This study aimed at evaluating reduction in intimal hyperplasia volume following angioplasty using sirolimus-eluting stents (Cypher) compared with thin-strut bare-metal stents (Pixel) in patients with small vessels. METHODS Eighty patients with coronary artery disease were prospectively included in two consecutive series, the first using sirolimus-eluting stents (50) and the second ...

OBJECTIVES We sought to determine predictors of restenosis after coronary stenting (CS) in a consecutive series of patients. BACKGROUND Although stenting in highly selected patient groups reduces restenosis, the results of stenting in a heterogeneous patient group and the effects of clinical and procedural factors on stent restenosis are currently unclear. METHODS We analyzed the 6-month an...

Coronary angioplasty has dramatically influenced the current practice of cardiology. Introduced only 10 years ago, it is now widely used as a means of revascularizing symptomatic patients with coronary artery disease. It is currently considered the optimal therapy for nearly one half of patients needing a revascularization procedure. Recent studies suggest that the technique can be satisfactori...

OBJECTIVES To determine the efficacy of coronary angioplasty as the sole method of revascularisation in patients with coronary artery disease and chronically dysfunctional but viable myocardium (hibernating myocardium), and to assess the effect of restenosis on functional outcome. DESIGN AND PATIENTS 24 consecutive patients with hibernating myocardium were studied. Positron emission tomograph...

Angioplasty is a safe and effective way to unblock coronary arteries. During this procedure, a catheter is inserted into the groin or arm of the patient and guided forward through the aorta and into the coronary arteries of the heart. There, blocked arteries can be opened with a balloon positioned at the tip of the catheter. Initially, angioplasty was performed only with balloon catheters, but ...

OBJECTIVE Diabetes mellitus is associated with high rates of restenosis and adverse outcomes after percutaneous transluminal coronary angioplasty (PTCA). It is unclear whether coronary stenting reduces adverse events in diabetic patients after PTCA. Our purpose was to determine whether coronary stenting improves clinical event rates in diabetic patients after PTCA. METHODS The Routine Versus ...