The effect of progressive increases in intraluminal glucose concentration on proximal tubule sodium absorption was studied in normal and streptozotocin diabetic rats by microperfusion. Each tubule was perfused twice, with and without glucose added to the perfusion fluid. Net sodium and water absorption were markedly enhanced by 300-500 mg% intraluminal glucose in both normal and diabetic rats. ...

for prolonging the time that drug remains in stomach, new methods used as floating drug delivery systems, that available in various forms such as floating tablets. these systems enhance drug absorption and decrease plasma concentration fluctuations. iron deficiency and its inadequate absorption in diet are of community health problems. for prolonging the time that drug remains in stomach, new m...

The purpose of this study was to determine the precise role of angiotensin subtype-1 (AT1) and -2 (AT2) receptors and the mechanisms by which they act to alter fluid transport in the rat jejunum. In rats on normal sodium intake, ANG II at low dose stimulated net jejunal fluid absorption, whereas at a high dose the peptide inhibited absorption. Low-dose ANG II-stimulated fluid absorption was blo...

We found mRNA for the three isoforms of the cyclic nucleotide-gated nonselective cation channel expressed in the mucosal layer of the rat intestine from the duodenum to the colon and in intestinal epithelial cell lines in culture. Because these channels are permeable to sodium and calcium and are stimulated by cGMP or cAMP, we measured 8-bromo-cGMP-stimulated sodium-mediated short-circuit curre...

The absorption of water, sodium, and potassium from isolated segments of the large intestine has been studied in 11 patients. In eight control segments adjacent to a carcinoma of the colon, absorption of water and sodium and secretion of potassium occurred. In five segments of intestine containing a villous papilloma, water, sodium, and potassium were secreted. The difference is mainly due to a...

Abstract Background and Aims Low sodium intake is associated with a lower blood pressure less proteinuria, which are important therapeutic targets in chronic kidney disease. In contrast, low potassium has been higher incidence of disease cardiovascular events. Counselling patients regarding their requires accurate estimation intake, but 24-hour urinary excretion can deviate substantially from a...

The purpose of this study is to summarize water, carbohydrate (CHO), and electrolyte absorption from carbohydrate-electrolyte (CHO-E) solutions based on all of the triple-lumen-perfusion studies in humans since the early 1960s. The current statistical analysis included 30 reports from which were obtained information on water absorption, CHO absorption, total solute absorption, CHO concentration...

The capacities of 16 proteins, after being subjected to electrophoresis on polyacrylamide gel containing sodium dodecyl sulphate, to bind Coomassie Brilliant Blue G 250 have been measured. It is observed that absorption is a linear function of the surface area of the protein in spherical (globular) configuration. The dye binding capacity of proteins has been used to determine the molar ratio in...