This experiment was conducted to evaluate the effects of caffeine and trans-cinnamaldehyde (TC) on growth performance, hematological parameters, stress hormones, immune response, and some blood parameters of broiler chickens. Three hundred fifty 1-d-old broiler chicks were randomly assigned to 7 dietary treatments (five pens/ treatment of 10 male broilers each) in a completely randomized desig...

Previous studies have shown that caffeine has beneficial effects on cognitive impairment in sleep deprived male rats. Therefore in the present study, we examined the effects of chronic caffeine administration on learning and memory impairments induced by sleep deprivation (SD) in the intact and ovarectomized (OVX) female rats. Two sets of animals including intact and OVX were randomly recruited...

Patients were randomly allocated to one of two groups; intravenous or epidural analgesia, with twenty patients in each group. General anesthesia was induced with thiopentone 5-6 mgkg-1 and maintained with 0.8-1.0% isoflurane and 66% nitrous oxide in 33% O2. The trachea was intubated after administration of vecuronium 0.1 mgkg-1. Patients in the epidural analgesia groups then received, by random...

Caffeine, pentoxifylline, and kallikrein are substances that affect the efficiency of sperms in the fertilization process; however, they have not been adequately studied. The present study aimed to examine the influence of caffeine, kallikrein, and pentoxifylline on sperm motility in bovine as well as investigate their optimum concentrations for increasing the movement of sperms in bovine. Froz...

5'-Adenosine monophosphate-activated protein kinase (AMPK) has been identified as a key mediator of contraction-stimulated insulin-independent glucose transport in skeletal muscle. Caffeine acutely stimulates AMPK in resting skeletal muscle, but it is unknown whether caffeine affects AMPK in contracting muscle. Isolated rat epitrochlearis muscle was preincubated and then incubated in the absenc...

a simple, sensitive, accurate and precise simultaneous uv spectrophotometric method has been developed for the estimation of carisoprodol, paracetamol and caffeine in tablet dosage form. the absorption maxima of the drugs were found to be 221, 248 and 273 nm for carisoprodol, paracetamol and caffeine respectively, in methanol, using a double beam uv/visible spectrophotometer. carisoprodol, para...

In this study, we investigated the impact of a controlled 4-day caffeine withdrawal period on the effect of an acute caffeine dose on endurance exercise performance. Twelve well-trained and familiarized male cyclists, who were caffeine consumers (from coffee and a range of other sources), were recruited for the study. A double-blind placebo-controlled cross-over design was employed, involving f...

BACKGROUND Caffeine acts mainly via blockade of adenosine receptors, which have been classified into A1, A2A, A2B, and A3 subtypes. We determined whether repeated caffeine administration (750 mg/d for 1 week) upregulates the human platelet A2A adenosine receptor and is accompanied by sensitization of platelet responses (increase in cAMP accumulation and decrease in platelet aggregation) to sele...

1. Caffeine reacts with haematin to form a caffeine-haematin compound that has a characteristic absorption spectrum. 2. Graphical analysis of the titration of haematin with caffeine shows that 2mol.prop. of caffeine split the dimeric haematin. 3. Thermodynamic parameters suggest that the reaction involves the making and breaking of hydrophobic bonds. 4. Graphical analysis shows dimeric haem to ...

Impact of 5 mg/kg caffeine, chance of receiving caffeine (stimulus expectancies), and expectations of effects of caffeine (response expectancies) on objective (heart rate (HR), systolic/diastolic blood pressure (SBP/DBP), measures of heart rate variability (HRV), and reaction time (RT)) and subjective variables were investigated in a double-blind, placebo-controlled experiment with a no-treatme...