A boy, aged 21 years, had befen suffering from irregular febrile attacks associated with enlarged spleen and liver and progressive anaemia for about nine months. After failure of oral treatment by drugs, the nature of which is not known to the writer, intravenous injection of urea stibamine (Brahmachari) were commenced by a local practitioner. The injections were given at intervals of three or ...

Leukotriene receptor antagonists, which are generally considered safe with a few adverse drug reactions, are increasingly used in the treatment of various allergic diseases, including asthma and allergic rhinitis. Although a few anaphylactic reactions to montelukast have been reported worldwide, there is still a lack of reports about severe adverse drug reactions associated with pranlukast. Her...

INTRODUCTION Hydatid cyst is a parasitic disease caused by a tapeworm Echinococcusgranulosus. Humans are accidental hosts and infected after digestion of foods contaminated to fecal matter of definite hosts. The most affected organs are liver and lungs. Rupture of cyst (spontaneous rupture or rupture due to trauma or surgery) can cause anaphylactic reactions. Even considered as a rare event dur...

Anaphylaxis is a systemic, type I hypersensitivity reaction that often has fatal consequences. Anaphylaxis has a variety of causes including foods, latex, drugs, and hymenoptera venom. Epinephrine given early is the most important intervention. Adjunctive treatments include fluid therapy, H (1) and H (2) histamine receptor antagonists, corticosteroids, and bronchodilators; however these do not ...

Anaphylactic shock is a severe allergic reaction involving multiple organs including the bronchial and cardiovascular system. Most anaphylactic mediators, like platelet-activating factor (PAF), histamine, and others, act through G protein-coupled receptors, which are linked to the heterotrimeric G proteins G(q)/G(11), G(12)/G(13), and G(i). The role of downstream signaling pathways activated by...

1. Attempts to produce anaphylactic shock in white rats by second intravenous or subdural injections of horse serum have failed. 2. It was impossible to demonstrate either by skin reactions or by the uterine reaction that white rats can be sensitized to horse serum. 3. It was not possible to sensitize guinea pigs passively with the serum of white rats presumably immunized to horse serum. 4. In ...

Paramedics found the woman to be in a state of pulseless electrical activity 20 minutes after the cardiovascular collapse. They immediately commenced an adrenaline infusion and performed cardiopulmonary resuscitation and intubation before transporting her to the emergency department. The adrenaline infusion was ceased after 3 hours, when she was deemed to be haemodynamically stable. On presenta...

Introduction Epidemiological data on anaphylaxis have been underestimated both in Poland and worldwide. Aim To evaluate the prevalence of anaphylaxis in Poland, including a classification by gender, age and residential region. Material and methods The data used in the analysis were derived from two sources, the National Health Fund records of healthcare services for 2008-2015 (official stat...