The syndrome of hereditary nephritis and perceptive deafness was first recognized by Alport (1927), although reports suggestive of this association date from the latter part of the i8th century. The syndrome has since been widened to include certain ocular defects, such as lenticonus, microspherophakia, and lens opacities, and about IOO families have been described in the world literature. In r...

Proteinuria is known to be associated with all-cause and cardiovascular mortality, nephrotic syndrome defined by the level of proteinuria hypoalbuminemia. With advances in medicine, new causative genes for genetic kidney diseases are being discovered increasingly frequently. We reviewed articles on proteinuria/nephrotic syndrome, focal segmental glomerulosclerosis, membranous nephropathy, diabe...