Background: Blood loss during and immediately after total knee arthroplasty (TKA) is among the most challenging concerns. It has been demonstrated that Tranexamic acid (TXA) can help to reduce perioperative blood loss. TXA can be used as an oral, topical or intravenous injection. Many studies evaluated the effectiveness of each route of administration but few works on a comparison between them....

The total number of 542 patients with colorectal cancer surgery have been analyzed in order to estimate the effect of receiving transfusion local recurrences, and the disease free - survival. It should be examined whether there are changes in general immunity indicators which would be connected with perioperative transfusion. A significant connection has been found between local recurrences and...

The importance of warming up the whole blood before transfusion , parti -cularly when large amounts of stored blood is used for patients in shock or under general anesthesia is discussed. Var­ious methods of Warming blood is presn­tcd and the use of high frequency Ele­ctromagnetic field for this purpose and its adv1mtagcs is introduced. 

the clinical significance of abo and rhesus blood group systems has been well documented. the objective of this study was to determine the frequency of abo and rhesus blood groups in blood donors in lahore, pakistan, with a view to generate data with multipurpose future practicalities in the field of medicine. blood groups of 3000 blood donors were determined by commercially available standard ...

A high-dose local tranexamic acid has been introduced in total knee arthroplasty for bleeding control. We are not sure about the systemic absorption and side effects. The aim of this study was to evaluate the effect of low dosage of intra-articular tranexamic acid injection combined with 2-hour clamp drain in minimally bleeding computer-assisted surgery total knee replacement (CAS-TKR). A prosp...

OBJECTIVE To compare the effects of crystalloid and colloid solutions, tranexamic acid and epsilon-aminocaproic acid on the need for allogenic blood transfusion and on coagulation and fibrinolysis parameters. METHODS We conducted the study in the Anesthesiology and Reanimation Department of Hacettepe University Medical Faculty, Ankara, Turkey between March 2004 and April 2005. The study inclu...

The purpose of this study was to retrospectively evaluate the efficacy a tranexamic acid (TXA) perioperative protocol for primary hip- and knee arthroplasty, in terms allogenic blood transfusion rates. A retrospective cohort conducted included all hip arthroplasty procedures period 2014-2019. Patients who underwent surgery due trauma or revision were excluded. total amount 5205 patients eligibl...