BACKGROUND Recent studies have suggested that epidermal barrier dysfunction contributes to the development of atopic dermatitis (AD) and other allergic diseases. OBJECTIVE We performed a prospective, randomized controlled trial to investigate whether protecting the skin barrier with a moisturizer during the neonatal period prevents development of AD and allergic sensitization. METHODS An em...

Atopic dermatitis is the most common chronic inflammatory disease among children in industrialised countries. Many factors influence this disease in a negative way and contact allergy is one such factor. The aim of the study was to examine the frequency of contact allergy among children with the diagnosis atopic dermatitis. Contact allergy was found in 22/82 children (26.8%), the most common fr...

BACKGROUND There is considerable concern about the rising trend in the prevalence of asthma and allergic diseases. The ability to monitor this trend would be enhanced by the use of a biological marker for these diseases. OBJECTIVE This study investigated whether serum interleukin (IL) 12 and IL-18 levels were associated with allergic symptoms such as those of asthma, allergic rhinitis, and at...

OBJECTIVES To investigate the rate of allergic diseases including asthma, allergic rhinitis and eczema in children and adolescents diagnosed with obsessive-compulsive disorder (OCD) (n:26) and/or Tourette syndrome (TS) (n:32) [OCD plus TS, n:13] compared to control subjects (n:35) [total, n:80]. PATIENTS AND METHODS The symptoms of any allergic disease were assessed using the ISAAC questionna...

INTRODUCTION Childhood asthma is one of important diseases of childhood. There is no known prevalence of asthma and allergic diseases in Lebanon. This study was conducted with a secondary objective of finding the odds of exposure to asthma, allergic rhinitis and eczema potential risk factors in Lebanese children. MATERIAL AND METHODS It is a cross-sectional study on children in public and pri...

Background: Atopic dermatitis is a prevalent health problem in the world. Allergic sensitization is an important risk factor, but the roles of other factors, inherent in tropic region, are unknown. Objective: A cohort study was designed in a tropical city to investigate molecular and environmental risk factors for eczema, considering as particular features perennial exposure to mites, poor li...

Dietary factors may be important in the development of atopic eczema. It remains controversial whether n-3 polyunsaturated fatty acid intake is preventive against allergic disorders and whether n-6 polyunsaturated fatty acid intake increases the risk of allergic disorders. The current cross-sectional study examined the association between intake of fatty acids and foods high in fatty acids and ...

BACKGROUND The role of timing and diversity of allergenic food introduction in the development of childhood allergic sensitization and atopic diseases is controversial. OBJECTIVE To examine whether timing and diversity of allergenic food introduction are associated with allergic sensitization, allergy and eczema in children until age 10 years. MATERIALS AND METHODS This study among 5,202 ch...

Sir, Dermatitis of the feet can be difficult to treat. Therapyresistant foot dermatitis is not limited to a particular type of dermatitis; it is encountered in allergic contact eczema, atopic eczema and endogenous forms. The key principle in the management of allergic contact dermatitis is avoidance of the relevant allergen; for example, chromate or rubber substances in the shoes. However, wear...