The effect of bretylium tosylate (BT) was determined in 27 consecutive cases of resistant ventricular fibrillation (VF) encountered by a hospital cardiac arrest team. The VF was sustained and completely resistant to multiple injections of lidocaine, sequential DC shocks at 400 watt-sec and one or a combination of intravenous propranolol, diphenylhydantoin or procainamide. Following 30 min of su...

The interest in thermogalvanic cells (TGCs) has grown because it is a candidate technology for harvesting electricity from natural and waste heat. However, the cost of TGCs has a major component due to the use of the platinum electrode. Here, we investigate new alternative electrode material based on conducting polymers, more especially poly(3,4-ethylenedioxythiophene)-tosylate (PEDOT-Tos) toge...

a simple, fast, efficient and environmentally friendly method for synthesis of benzimidazole and its 2-alkyl, aryl and heteroaryl substituted derivatives was developed using zeolite hy. two component cyclolcondensation of 1,2-phenylenediamine (o-phenylenediamine) and commercially available carboxylic acids catalyzed by zeolite hy without any solvent, under microwave irradiation led to formation...

It has recently been demonstrated that the chemotactic peptide N-formyl-Met-Leu-Phe activates phospholipase D (PLD) in dimethyl sulfoxide-differentiated HL-60 granulocytes to produce phosphatidic acid (PA) and, in the presence of ethanol, phosphatidylethanol (PEt) (Pai, J.-K., Siegel, M. I., Egan, R. W., and Billah, M. M. (1988) J. Biol. Chem. 263, 12472-12477). We now report that biologically ...

The possibility of homoallylic participation in solvolyses of substituted cyclopent-3-en-1-yl sulfonates has been investigated. Relative rates of solvolyses of 2,2,5,5-tetramethylcyclopentyl (6), 2,2,3,4,5,5-hexamethylcyclopent-3-en-1-yl (13), 2,2,5,5-tetramethyl-3,4-bis(methylene)cyclopent-l-y1 ( 6), and 2,2,5,54etramethylcyclopent-3-en-1-yl (18) tosylates in 80% (v/v) ethanol/water at 95 "C a...

We sought to identify whether reductions in cutaneous active vasodilation during simulated orthostasis could be assigned solely to cardiopulmonary or to carotid baroreflexes by unloading cardiopulmonary baroreceptors with low levels of lower body negative pressure (LBNP) or unloading carotid baroreceptors with external pressure applied over the carotid sinus area [carotid pressure (CP)]. Skin b...

Cu-catalyzed cross-coupling of unactivated secondary alkyl iodides with alkyl Grignard reagents in the presence of 1,3-butadiene as a ligand precursor was developed. The use of 1,3-butadiene resulted in improved yields of alkyl-alkyl products with improved selectivities.