The objective of this study was to develop thin, biocompatible, and biofunctional hydrogel-coated small-sized nanoparticles that exhibit favorable stability, viability, and specific cellular uptake. This article reports the coating of magnetic iron oxide nanoparticles (MIONPs) with covalently cross-linked biofunctional polyethylene glycol (PEG) hydrogel. Silanized MIONPs were derivatized with e...

Dip-pen nanolithography is used to selectively modify the SiOx area between microfabricated electrodes. The modified surface is characterized by atomic force microscopy, X-ray photoelectron spectroscopy, force volume imaging, and adhesion maps. The functionalized complex architecture is used for the localization of DNA coated with magnetic nanoparticles. The strategy reported here can become th...

Normal micelle microemulsion method was utilized for fabrication of organically modified silica (ORMOSIL) nanoparticles. The void and dye-doped nanoparticles were synthesized in nonpolar core of two different surfactants including Aerosol OT and Tween 80. The nanoparticles were characterized using transmission electron microscopy, dynamic light scattering, and zeta potential analysis. Our resul...

Ultrasound micro-molding technology has proved useful in processing biodegradable polymers with minimum material loss. This makes this technology particularly suitable for the production of biomedical microdevices. The use of silica (SiO2) nanoparticles is also interesting because of advantages like low cost and enhancement of final properties. Evaluation of the capacity to create a homogeneous...

Monodisperse small iron oxide nanoparticles functionalized with dendritic polyglycerol (dPG) or dendritic polyglycerol sulfate (dPGS) are prepared. They are highly stable in aqueous solutions as well as physiological media. In particular, oleic acid capped iron oxide particles (core diameter = 11 ± 1 nm) were modified by a ligand exchange process in a one pot synthesis with dPG and dPGS bearing...

Bifunctional magnetic-fluorescent composite nanoparticles (MPQDs) with Fe(3)O(4) MPs and Mn:ZnS/ZnS core-shell quantum dots (QDs) encapsulated in silica spheres were synthesized through reverse microemulsion method and characterized by X-ray powder diffraction, scanning electron microscopy, transmission electron microscopy, vibration sample magnetometer, and photoluminescence (PL) spectra. Our ...

This contribution presents the production of polymer-coated iron oxide magnetic nanoparticles carrying functional groups on their surface and their basic characterization. The preparation of polymer-coated nanoparticles was carried out by a two-step process. In the first step, magnetite (Fe3O4) nanoparticles were prepared by a co-precipitation method from the solutions of FeCl2.4H2O and FeCl3.6...

In this article, a systematic study of the design and development of surface-modification schemes for silica nanoparticles is presented. The nanoparticle surface design involves an optimum balance of the use of inert and active surface functional groups to achieve minimal nanoparticle aggregation and reduce nanoparticle nonspecific binding. Silica nanoparticles were prepared in a water-in-oil m...

Trypsin has been encapsulated in the mesopores of a hierarchical mesoporous silica material synthesized via Cu(I) catalyzed azide-alkyne click reaction between azide functionalized large spherical SBA-15 particles and alkyne functionalized mesoporous silica nanoparticles (MSNs). Encapsulated trypsin functions as an efficient biocatalyst and can be recycled several times.

synthesis and characterization of two functionalized gold nanoparticles by using of two poly functional amino acids (l-arginine and l-aspartic acid) are reported. the gold nanoparticles were reduced by sodium citrate and functionalized with l-arginine at the ph of 7 and 11 and l-aspartic acid at the ph of 7. transmission electron microscopy, uv-vis spectroscopy, dynamic light scattering, zeta p...