BACKGROUND Acute lung injury (ALI) induced by cardiopulmonary bypass (CPB, CPB-ALI) is a common and serious complication after cardiac surgery. And infants and young children are more prone to CPB-ALI. The purpose of this study was to investigate the perioperative changes of plasma gelsolin (pGSN) in patients below 3 years of age with cardiac surgeries and CPB, and determine whether pGSN are as...

undoubtedly the founder of any knowledge is who laid the cornerstone of that. on the base of many narratives, imam ali (as) is the founder of arabic grammar who directed abul asvad addoali to expand arabic grammar. but some of modern scholars imitated some orientalists and on the base of a few narratives denied that the founder of arabic grammar is imam ali (as). they also refused to accept the...

Acute lung injury (ALI) remains a major cause of morbidity and mortality in critically ill patients. Despite improved understanding of the pathogenesis of ALI, supportive care with a lung protective strategy of mechanical ventilation remains the only treatment with a proven survival advantage. Most clinical trials in ALI have targeted mechanically ventilated patients. Past trials of pharmacolog...

Human Neutrophil Elastase (HNE) is one of the main proteases secreted into the alveolar space by infiltrated neutrophils during several inflammatory lung diseases such as cystic fibrosis, acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Consequently, a number of therapeutic approaches based on the specific inhibition of HNE are currently under investigation. The present w...

Acute lung injury (ALI) is a critical illness syndrome with a mortality rate of 25-40%. Despite recent advances of our understanding of the pathophysiology of ALI, no pharmacologic therapies have been proven effective. The key pathogenesis of ALI is the activation of the coagulation cascade and impaired fibrinolysis, resulting in extensive fibrin and hyaline membrane deposition. Activated prote...

We solve the integral equation describing the propagation of light in an isothermal plane-parallel atmosphere of optical thickness τ∗, adopting a uniform thermalization parameter ǫ. The solution given by the ALI method, widely used in the field of stellar atmospheres modelling, is compared to the exact solution. Graphs are given that illustrate the accuracy of the ALI solution as a function of ...

INTRODUCTION The aim of this study was to describe the epidemiology and management of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) in Ireland. METHODS As part of a 10-week prospective national audit of patient demographics and organ failure incidence in intensive care in Ireland, all patients with ALI/ARDS in 14 participating centres were prospectively identified...

Background: Acute lung injury (ALI) and its extreme manifestation the acute respiratory distress syndrome (ARDS) complicate a wide variety of serious medical and surgical conditions. Thioredoxin is a small ubiquitous thiol protein with redox/inflammation modulatory properties relevant to the pathogenesis of ALI. We therefore investigated whether thioredoxin is raised extracellulary in patients ...

Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no model of malaria-induced lung injury has been definitively established. This study used bronchoalveolar lav...

Property concepts across categories Adjectival meanings—known in the typological literature as property concepts (PCs)—are lexicalized in two ways in the Senegambian language Wolof: i) via stative verbs (PCVs) denoting relations between individuals and properties (1); ii) via mass nouns, denoting the abstract properties themselves (PCNs) (2). (1) PCVs: xonq/njool/bees/baax/rafet red/tall/new/go...