Benign Prostatic Hyperplasia (BPH) merupakan keadaan kondisi terjadinya penyumbatan yang terlihat pada pembesaran prostat jinak dengan tampilan histologis adenoma menyebabkan obstruksi bervariasi atau tanpa gejala. Kejadian komplikasi biasa ditimbulkan oleh BPH adalah sistitis dan anemia. Pembesaran jaringan tinggi akan penekanan uretra pars prostatika lumen mengakibatkan obstruksi. Tujuan: unt...

background: premature ejaculation (pe) is the most common sexual disorder in men and studies reported prevalence up to 30% (1, 2). pe is not a life-threatening medical condition but it influences the quality of life (qol). objectives the aim of this study was to compare the efficiency, and safety of alpha blocker drugs in the treatment of patients with premature ejaculation (pe). additionally w...

A composite gastro-retentive matrix for zero-order delivery of highly soluble drug alfuzosin hydrochloride (10mg) has been designed and characterized. Two systems containing polyethylene oxide (PEO), hydroxypropylmethylcellulose (HPMC), sodium bicarbonate, citric acid and polyvinyl pyrrolidone were dry blended and compressed into triple layer and bi-layer composite matrices. Dissolution studies...