background and objectives : the attempts were made to describe the development of a whole cell immobilization of p. pastoris by entrapping the cells in polyacrylamide gel beads. the alcohol oxidase activity of the whole cell pichia pastoris was evaluated in comparison with yeast biomass production. materials and methods : methylotrophic yeast p. pastoris was obtained from collection of standard...

Background. Effective psychological treatment, including cognitive behavioral therapy and motivational interviewing (MI), is available for people with problematic gambling behaviors. To advance the development of treatment for gambling disorder, it is critical to further investigate how comorbidity impacts different types of treatments. The purpose of this study was to investigate whether scree...

Autoscopic phenomenon, a psychic illusionary duplication of one's own self, has been the subject of interest in the literature and science for years. It has been reported in various diseases of the central nervous system but with an unknown mechanism. Hallucinations are a common presentation in alcohol dependence syndrome during delirium tremens and as induced disorder. However, autoscopic hall...

285 Fetal Alcohol Syndrome (FAS), a devastating developmental disorder resulting from heavy maternal alcohol consumption during pregnancy, was first identified in France in 1968 (Lemoine et al. 1968) and in the United States in 1973 (Jones et al. 1973). FAS can be readily diagnosed shortly after birth when characteristic facial features and growth retardation are present, coupled with known pre...

Background: About 40 thousand newborns are delivered annually with fetal alcohol syndrome (FAS). It induces serious CNS complications. Methods: In a review of, the word “fetal alcohol syndrome” was searched in PubMed and Google Scholar and the retrieved articles were summarized. Results: Many studies showed that alcohol can cause more defects in fetus than heroin, cocaine and marijuana. The pos...

Seasonal changes in mood and behavior (seasonality) may be closely related to alcoholism. Some patients with alcoholism have a seasonal pattern to their alcohol misuse. They may be self-medicating an underlying seasonal affective disorder (SAD) with alcohol or manifesting a seasonal pattern to alcohol-induced depression. Both genetic and environmental factors play a role in the etiology and pat...

OBJECTIVE To analyse mortality and life expectancy in people with alcohol use disorder in Denmark, Finland and Sweden. METHOD A population-based register study including all patients admitted to hospital diagnosed with alcohol use disorder (1,158,486 person-years) from 1987 to 2006 in Denmark, Finland and Sweden. RESULTS Life expectancy was 24-28 years shorter in people with alcohol use dis...

ALCOHOLISM AND THE ALCOHOL USE DISORDERS 620 HISTORICAL INTRODUCTION AND ISSUES FOR THE FIELD 621 EPIDEMIOLOGY 623 A MULTILEVEL NET FOR DEVELOPMENTAL VARIATION 625 VARIATIONS IN RISK AND COURSE OF THE DISORDER 628 Differences in Alcohol Nonspecific-Risk Structure for Later Disorder Are Present in Early Childhood 629 Heterogeneity in the Course of Risk and Heterogeneity of Nonspecific Risk 632 H...

Emerging evidence has displayed that oxygen free radicals especially ones promoted by "free" iron play an important role in the development of alcoholic liver disease (ALD). Naturally-occurring quercetin has been reported to prevent ALD and iron overload-induced damage aside from the "free" iron. The purpose was to explore the potential mechanisms by which quercetin arrests alcohol-induced "fre...