The infection risk of biomaterials implants varies between different materials and is determined by an interplay of adhesion and surface growth of the infecting organisms. In this study, we compared initial adhesion and surface growth of Staphylococcus epidermidis HBH(2) 102 and Pseudomonas aeruginosa AK1 on poly(dimethylsiloxane), Teflon, polyethylene, polypropylene, polyurethane, poly(ethylen...

Biomaterial-centered infection is a dreaded complication associated with the use of biomedical implants. In this paper, the antimicrobial activity of silicone rubber with a covalently coupled 3-(trimethoxysilyl)-propyldimethyloctadecylammonium chloride (QAS) coating was studied in vitro and in vivo. Gram-positive Staphylococcus aureus ATCC 12600, Staphylococcus epidermidis HBH, 102, and Gram-ne...

SOURCE/DESCRIPTION; A 4.5 kb (pMCT96.1) or a 3.7 kb (pMCT96.2) of Mspl fragment from cosmid MCT96 isolated by an oligonucleotide (GTGTGTGTGTGTGTGTGTGT) (1) was subcloned into the Accl site of pUC18. POLYMORPHISM: pMCT96.1 : Rsal identifies 3 systems of site polymorphisms; system 1: 4.7 kb (Rl) or 3.7 kb (R2); system 2: 3.0 (R3) kb or 2.8 kb (R4); system 3: 1.0 kb (R5) or 0.9 kb (R6) pMCT96.2 : ...

The real algebraic set we obtain will in general be singular. The homeomorphism will be piecewise differentiable. Total algebraicity is a very useful concept since it eiliminates many obstructions to making a topological situation algebraic, c.f. [AK1], [AK2], [AK5]. At first glance our result does not seem to be very useful since current algebraic approximation lemmas require nonsingularity. T...

A classical result of Arnold and Brieskorn [Bk], [Bk2] states that the complement of the discriminant of the versal unfolding of a simple hypersurface singularity is a K(π, 1). Deligne [Dg] showed this result could be placed in the general framework by proving that the complement of an arrangement of reflecting hyperplanes for a Coxeter group is again a K(π, 1) (and more generally for simplicia...

Schistosomiasis, a disease caused by the trematodes of the Schistosoma genus, affects about 240 million people worldwide. The Praziquantel (PZQ) is the drug used to treat this disease. However, reports of resistant strains reinforce the need to develop a new schistosomicidal drug. The study of new drugs and vaccines that can contribute to the control of this pathology becomes urgent. A new appr...

The 4.2 ka event at the Mid- to Late-Holocene transition is often regarded as one of largest and best documented abrupt climate disturbances Holocene. most clearly manifested in Mediterranean Middle East a regional dry anomaly beginning abruptly 4.26 kyr BP extending until 3.97 BP. Yet impacts this drought are extended other regions sometimes globally. In particular, nature spatial extent tropi...

BACKGROUND AND PURPOSE In patients with stroke and long-standing hypertension, the autoregulation curve of cerebral blood flow (CBF) shifts toward higher blood pressure levels. Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure and shift the autoregulation curve back to normal in hypertensive patients. ACE inhibitors have 2 major pharmacological properties: they inhibit both t...

There have been efforts to overcome the problem in treatment of cancer using medicinal plants. It has been shown that Citrus essential oil of contains different terpens with antitumor activities. In this study we sought to determine the cytotoxicity of essential oils of Iranian Citrus limon (L.), C. medica (L.), C. sinsensis (L.) peels on cancer cell lines. Essential oils were prepared by hydr...