We present a patient with cryptogenic focal epilepsy and another with Dravet syndrome, who experienced seizure aggravation and negative myoclonus, associated with continuous spikes and waves during slow sleep, induced by levetiracetam. For both patients levetiracetam was discontinued, and there was significant improvement of this particular electroclinical picture.

Pathophysiology of aggravation and death due to heat illness includes high fever, circulatory failure and systemic inflammatory response syndrome (SIRS), as well as disseminated intravascular coagulation (DIC) and multiple organ failure. DIC and multiple organ failure are the important determinants of severity and mortality of heat

Ventricular fibrillation developed in a 19 year old woman taking the antihistamine astemizole. She was successfully resuscitated. QTc prolongation was found and persisted despite withdrawal of the drug. Aggravation of congenital long QTc syndrome by astemizole is postulated. More caution should be exercised with the use of this drug.

CLINICAL INTRODUCTION A 48-year-old male patient with a history of New York Heart Association (NYHA) Class II dyspnoea for the last 2 years presented with acute onset breathlessness associated with orthopnoea and palpitations. The symptom aggravation was abrupt with simultaneous occurrence of both dyspnoea and palpitations. After medical stabilisation, the neck pulsations were as shown in onlin...

*Correspondence: S. Lata. Department of Zoology, MMV, Banaras Hindu University, Varanasi, 221005, U.P, India. Tel.: +91 9415301826. Fax: +91 5422367927. E-mail: [email protected]. K. N. Tiwari. Department of Botany, MMV, Banaras Hindu University, Varanasi, 221005, U.P, India. Tel.: +91 9335668374. Fax: +91 5422367927. E-mail: [email protected] Aggravation of cyclophosphamide-induced r...

background dyspepsia is a common symptom with an extensive differential diagnosis and a heterogeneous pathophysiology. many studies have reported that dyspeptic symptoms are associated with ingestion of some foods. current treatments for functional dyspepsia have generally ignored the potential role of diet. method this cross-sectional study was done at the gastroenterology department of shahid...