Selection intensity and generation interval were evaluated in a Hereford cattle herd made up of 14 inbred lines and 14 linecross groups corresponding to the lines of inbred sires at the Suan Juan Basin Research Center, Hesperus, Colorado. Selection indexes practiced were calculated in retrospect. Analyses of the records collected from 1946 through 1973 involved weaning weight (WW) and postweani...

CONTEXT Long-term follow-up data on cognitive and motor functioning in adult patients with congenital hypothyroidism, diagnosed by neonatal screening, are scarce. Hence, it is still unclear whether the frequently reported cognitive and motor deficits observed during childhood persist in adulthood. OBJECTIVE The objective of this study was to examine cognitive and motor functioning in young ad...

BACKGROUND The prevalence of colorectal lesions in persons 40 to 49 years of age, as identified on colonoscopy, has not been determined. METHODS We reviewed the procedure and pathology reports for 906 consecutive persons 40 to 49 years of age who voluntarily participated in an employer-based screening-colonoscopy program. The histologic features of lesions that were identified and removed on ...

Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persistent PTDM patients, they were characterized by younger age at the time of transplantation (49+/-...

Review content summary This systematic review of 117 studies aimed to determine the risks and benefits of mammography screening for women 40 to 49 years of age. Participants studied were women 40 to 49 years of age. To be included, studies were systematic reviews, randomized-controlled trials, and observational studies. When possible, reviewers focused on evidence from studies featuring specifi...

BACKGROUND microRNAs (miRNAs) play a critical role in tumorigenesis, either as a tumor suppressor or as an oncogenic miRNA, depending on different tumor types. To date, scientists have obtained a substantial amount of knowledge with regard to miRNAs in pancreatic cancer. However, the expression and function of miR-371-5p in pancreatic cancer has not been clearly elucidated. The aim of this stud...

SIR, Traditionally osteoarthritis (OA) has been considered a process involving a disturbance of the normal balance between degradation and repair in the articular cartilage and subchondral bone. In contrast to rheumatoid arthritis where inflammation, both local and systemic, is a key feature, OA is considered a primarily non-inflammatory condition. The clinical signs of lowgrade inflammation th...

the aim of this study was to examine the effect of 12 weeks of concurrent training on rbp4 andinsulin resistance levels in obese middle-age men. for this purpose, 20 obese middle-age men voluntarily participated in this study and were assigned to concurrent training group (n=10, mean age 51.2 ± 2.25 yr and bmi 31.44 ± 0.81 kg/m²) and control group (n=10, mean age 50.3 ± 2.11 yr and bmi 30.32 ± ...

Pregnancy rate, calving interval, birth weight, weaning weight, and quarterly BCS were collected for 5 consecutive years on 454 fall-calving multiparous British crossbred cattle (3 to 10 yr of age) to evaluate associations of age with BCS and production parameters. Body weight and BCS were collected pre-calving, prebreeding, at weaning, and midway through the second trimester of pregnancy (Augu...