Multiple myeloma is uncommon in individuals younger than 40 years. Renal involvement is common in this disease, but acute tubulointerstitial nephritis is very rare. In 20% of patients, only the light chain is produced and serum protein electrophoresis is normal; however, in urine protein electrophoresis of these patients, the M spike is present. We reported a case of multiple myeloma in a 39-ye...

Proteomics can be defined as the large-scale analysis of proteins. Due to the complexity of biological systems, it is required to concatenate various separation techniques prior to mass spectrometry. These techniques, dealing with proteins or peptides, can rely on chromatography or electrophoresis. In this review, the electrophoretic techniques are under scrutiny. Their principles are recalled,...

The advent of 'NHS Direct', has centred attention on nurses giving telephone advice as part of the provision of out of hours medical care. A three month retrospective study of telephone consultations by nurses at the MRS Sennelager showed that telephone consultation greatly contributes to "out of hours" medical care. The outcome of telephone consultations made out of hours revealed that in 70% ...

The management of mobile objects like cars, persons, or workpieces in a factory is an important task in many context-aware environments. So far, most solutions can either cope with many small objects (few properties) or with a limited number of complex objects in a centralized way. In this paper, we face the challenge of managing a large number of bulky mobile objects (flying elephants). We sta...

no signs of emerging in response to this pressure, I turned to capsulotomy. And though I do not consider myself an over-nervous surgeon, I confess to have felt a slight feeling of nervousness in every case. The majority of surgeons still adhere to the old operation^ in spite of secondary cataracts. Mr. Eason in the Lancetof July 29th, 1911, gives 30?50 per cent, as the average rate of secondary...

This paper demonstrates the wide variety of systems for the analysis of posterior capsular opacification (PCO). No single system has been proved to be a gold standard and it is difficult to comment on the advantages of one system over another with the limited current knowledge on the effects of PCO on vision. There are few studies that actually compare the different systems of analysis. Researc...

proteins are fundamental components of cells which mediate many essential biological processes. proteomics is a rapidly growing field for the study of proteome, the protein complement expressed by the genome of an organism or cell type. the large-scale analysis of proteins leads to a more comprehensive view of molecular and cellular pathways that improves the overall understanding of the comple...

deproteinisation with acetonitrile (along with methanol or other reagents) is a useful and rapid technique in analysis of drugs or their metabolites in human serum. in this paper application of this simple technique in biopharmaceutical analysis using capillary electrophoresis (ce) is evaluated. some drugs with different ionic and protein binding properties were selected and dissolved in human ...