background: aflatoxins are the most common mycotoxins that contaminate crops. they are produced by fungi such as aspergillus flavus and aspergillus parasiticus . wheat ( tricitumaestivum ) is one of the most important staple foods used in iran, and the environmental conditions in the north of iran are favorable to fungal growth. this study was designed in order to determine the aflatoxin concen...

AbstractPregnant women and their developing fetuses are vulnerable to multiple environmental insults, including exposure to aflatoxin, a mycotoxin that may contaminate as much as 25% of the world food supply. We reviewed and integrated findings from studies of aflatoxin exposure during pregnancy and evaluated potential links to adverse pregnancy outcomes. We identified 27 studies (10 human cros...

We have examined the time course and patterns of covalent aflatoxin B^DNA adducts produced within the ribosomal RNA gene sequences isolated from the liver nuclear DNA of aflatoxin Bi-treated animals. Liver nuclear DNA was initially enriched in ribosomal DNA by cesium salt density centrifugaron, and incu bated under alkaline conditions to stabilize bound aflatoxin ST ONA moieties. Alkali-treated...

Administration of[3H]aflatoxin B2 (2,3-dihydroaflatoxin B1)(AFB2) to male rats resulted in levels of hepatic DNA- and ribosomal(r)RNA-aflatoxin adducts that were about 1% of those for rats given [3H]aflatoxin B1(AFB1). The levels of hepatic protein-aflatoxin adducts were 35 to 70% as great for AFB2-treated as compared to AFB1-treated rats...

During 2011~2013, a total of 729 samples for 19 types of medicinal plant were collected from Seoulyekryungsi in Seoul, Korea, and investigated for the presence of aflatoxins. The samples were analyzed using immunoaffinity column cleanup and high-performance liquid chromatography coupled to a fluorescence detector after post-column derivatization. Aflatoxins were found in 124 out of the 729 anal...

Occurrence of aflatoxins in crops has vast impacts on human health. Therefore, the study of aflatoxin biosynthesis has become important. Previous studies have shown that the aflatoxin biosynthesis gene cluster and several genes, enzymes, and regulatory elements are involved in aflatoxin biosynthesis; however, the intricate metabolic regulatory networks of aflatoxin synthesis remain unclear. Rap...

West African Aspergillus flavus S isolates differed from North American isolates. Both produced aflatoxin B1. However, 40 and 100% of West African isolates also produced aflatoxin G1 in NH4 medium and urea medium, respectively. No North American S strain isolate produced aflatoxin G1. This geographical and physiological divergence may influence aflatoxin management.

background: due to the high toxicity of aflatoxin and its effects on public health, determination of aflatoxin level in wheat flour samples in the golestan province, north of iran was investigated. to examine the effect of seasonal changes, summer and winter sampling was performed with standard sampling methods. methods: a total of 200 flour samples were collected from 25 factories. hplc method...

In this study, we investigated the binding ability of Saccharomayces cerevisiae to aflatoxin in pistachio nuts. The obtained results indicate that S. cerevisiae has an aflatoxin surface binding ability of 40% and 70% (with initial aflatoxin concentrations of 10 and 20 ppb) in the exponential phase. Acid treatments increase this ability to approximately 60% and 73% for the two concentrations of ...