Using high-pressure liquid chromatography (HPLC) and gas-liquid chromatography/mass spectrometry (GLC/MS), we have confirmed the existence of several sialic acid modifications in the adult rat and human colon. The major O-acetylated sialic acid in both species is 9-O-acetyl-N-acetylneuraminic acid; N-glycolylneuraminic acid is a major component of the adult rat colon. Both of these major modifi...

background: in the present study, the submandibularsalivary gland microscopic morphology of the adult africangiant pouched rat was investigated. this study was carried out toprovide the basic histology of this organ in the giant pouched rat,to accompany the dearth of information of its microscopicarchitecture in the available literature. this becomes of evenhigher importance when considering th...

1. Enzymic esterifications of 2-(N-hydroxyacetamido)fluorene and several other hydroxamic acids by liver cytosol were studied. Determination of 2-acetamido-3-methylthiofluorene was used for the assay. 2. With rat liver cytosol, requirement for ATP, Mg(2+) and SO(4) (2-) suggested formation of phosphate and sulphate esters of 2-(N-hydroxyacetamido)fluorene. 3. Rats showed sex and age differences...

Fractionation of testicular extracts and serum on a Concanavalin A-Sepharose column resolved two peaks of immunoreactive rat androgen binding protein. The rat androgen binding protein in the first peak, designated Form I, was present in the void volume; the other, designated Form II rat androgen binding protein, was bound by the column and specifically eluted by alpha-methylmannoside. In the co...

Introduction: Aggressive behavior is a major issue in the field of mental health. Pharmacotherapy is often used for the treatment of violent individuals. A neurochemical system most consistently linked with aggression is the GABAergic system. The aim of the present investigation was to examine the effect of muscimol (GABAA agonist) 250 and 500 ng/rat and picrotoxin (GABAA antagonist) 1.5 and...

E RYTHROPOIESIS IN THE NEWBORN RAT is in many respects analogous to that seen during the fifth-sixth month of gestation in human beings. Thus, up until birth, the red cell production in the rodent is predominantly hepatic and only at birth does significant myeloid erythropoiesis commence. This appeared to offer the opportunity to evaluate regulation of fetal red cell production. Initially we ob...

Background: Matricaria chamomilla (chamomile) is a herb used to treat various human illnesses. The present study was conducted to investigate the effects of chamomile extract on spermatozoon quality, serum levels of estradiol and testosterone, and sperm tail length in male adult rat.  Methods: Male Sprague-Dawley rats received extract of chamomile (400 mg/kg once daily, orally) during an 8-week...

Introduction: In adult mammalian brain, neural stem cells are isolated from both the dentate gyrus and subventricular zone. This study aimed to isolate neural stem cells from adult rat subventricular zone and differentiate them into neurons and astrocytes.  Methods: In this study, the whole brain was removed after full anesthesia and creating cervical dislocation. Under a microscope, subv...