OBJECTIVE To examine the expression and localisation of adrenomedullin in human coronary atherosclerotic lesions from patients with unstable angina (UAP) and stable angina (SAP), and to study the relation between adrenomedullin expression and plaque instability. DESIGN A retrospective observational study. PATIENTS Directional coronary atherectomy samples were obtained from 15 patients with ...

Adreno gonadal hypothalamo hypophyseal axis was tested in female monogamous bird domestic pigeon Columba livia domestica,. Two neurotransmitter precursor drugs (5-HTP and L-DOPA) were used at different time intervals. Female birds were divided in to three groups, having eight individuals in each group. Group 1 was control group received only vehicle. Group II was 0 hr group administered with 5-...

Huntington's disease (HD) is characterized by a triad of motor, psychiatric and cognitive symptoms. Although many of these symptoms are likely to be related to central nervous system pathology, others may be due to changes in peripheral tissues. The R6/2 mouse, a transgenic model of HD expressing exon 1 of the human HD gene, develops progressive alterations in the hypothalamic-pituitary-adrenal...

-This paper evaluate the development of low cost security system in the area where there is need of continuous monitoring using PIR (pyroelectric infrared) sensor. A special type of human sensor PIR is used to detect the human being around 20 feet distance. This sensor uses the concept of Black Body Radiation. If anyone tries to cross the area means the sensor detects and it sends a signal to t...

Abstract Stressful stimuli evoke a complex response mediated by two systems: the Sympathetic-Adreno-Medullar (SAM) axis and Hypothalamus-Pituitary-Adrenal (HPA) axis. Among factors involved in stress, glucocorticoids catecholamines secreted from adrenal glands sympathetic nerves are main effectors of physiological adaptations to stressors. Besides these, prolactin (PRL) is another hormone under...

Abnormal expression of membrane receptors has been previously described in benign adrenocortical neoplasms causing Cushing's syndrome. In particular, we have observed that, in some adreno corticotropic hormone (ACTH)-independent macronodular adrenal hyperplasia tissues, cortisol secretion is controlled by ectopic serotonin(7) (5-HT(7)) receptors. The objective of the present study was to invest...

5-hydroxytryptophan (5-HTP) is a direct 5-hydroxytryptamine (5-HT) precursor used to assess central serotonergic function. Its use has been limited by a narrow window between neuroendocrine changes and side effects, and variable kinetics related to inconsistent administration modes. By combining 5-HTP with carbidopa (CBD), increased bioavailability for brain penetration and decreased peripheral...

It was previously reported by the authors (1) that, in a normal rat with daily administration of 100 mg/kg borneol and intraperitoneal injection of 400 mg/kg glucuro nolactone for the period of 13 days, the amounts of total glucuronic acid, of o-glucuronide and of 1-ascorbic acid excreted in rat's urine, increased significantly, and that, in a bilate rally adrenalectomized rat administrated dai...