Primary pancreatic lymphoma is a rare extranodal manifestation of any histopathologic subtype of B cell non-Hodgkin's lymphoma that predominantly involves the pancreas. It comprises less than 0.2% of pancreatic malignancies and less than 0.7% of non-Hodgkin's lymphomas. This lymphoma is almost never suspected clinically. It is usually diagnosed by surgical exploration for suspected adenoca...

Colorectal carcinoma is a common malignancy in India as well as in world. Inspite of its high metastasizing ability to various organs and lymph node, orbital metastasis is exceptional. Very few cases have been reported in the world literature. We report orbital metastasis in a case of moderately differentiated rectal adenocarcinoma in a 58-year male patient from India in 2015. We want to focus ...

Sweat gland adenocarcinoma is a relatively uncommon malignancy. Clinical features are painless red or violet papules and nodules that can occasionally become ulcerated. The biological behavior is aggressive and metastatic sweat gland carcinoma spreads through the lymphatic. The treatment of choice is wide surgical excision with regional lymph node dissection. The portrayed ase was a 60-year-old...

Pancreatic adenocarcinoma is one of the most leading causes of cancer-related deaths worldwide. Although recent advances provide various treatment options, pancreatic adenocarcinoma has poor prognosis due to its late diagnosis and ineffective therapeutic multimodality. Gemcitabine is the effective first-line drug in pancreatic adenocarcinoma treatment. However, gemcitabine chemoresistance of pa...

Pulmonary adenocarcinoma is a common malignancy that often involves calcification; however, bone formation in primary lung adenocarcinoma is extremely rare. In ten cases of primary pulmonary adenocarcinoma with heterotopic ossification, we detected immunoreactivity against TGF-beta1, osteopontin, osteocalcin and Runx2 in the fibroblastic stroma and tumor cells within the area of ossification. O...

Primary adenocarcinoma of the urinary bladder is a rare neoplasm sometimes causing diagnostic challenge because it can be indistinguishable morphologically from adenocarcinoma secondarily involving the bladder by metastasis or direct extension. Identifying the primary origin of the tumor is important in staging, determining appropriate therapy and assessing prognosis. We report herein a case of...

On necropsy of a 24 months age Dutch female rabbit the uterine horns seems enlarged with a nodular appearance. On the cut surface of the uterus as well as heart wall, white firm masses with a cauliflower- like surface was observed. No other important gross lesions were found in other organs. In histopathological examination of the uterus typical microscopic changes were those of adenocarcinoma....

Non-motile cilia are thought to be important determinants of the progression of many types of cancers. Our goal was to identify patterns of cilia gene dysregulation in eight cancer types (glioblastoma multiforme, colon adenocarcinoma, breast adenocarcinoma, kidney renal clear cell carcinoma, lung squamous cell carcinoma, lung adenocarcinoma, rectal adenocarcinoma, and ovarian cancer) profiled b...

Gastric adenocarcinoma, a single heterogeneous disease with multiple epidemiological and histopathological characteristics, accounts for approximately 10% of cancers worldwide. It is categorized into four histological types: papillary adenocarcinoma (PAC), tubular adenocarcinoma (TAC), mucinous adenocarcinoma (MAC), and signet ring cell adenocarcinoma (SRC). Effective differentiation of the fou...

To investigate the performance of combined 18F-FDG Positron Emission Tomography/Computed Tomography with high-resolution CT for differentiating invasive adenocarcinoma from adenocarcinoma in situ (pre-invasive lesion) or minimally invasive adenocarcinoma in stage IA lung cancer patients with solitary ground-glass opacity nodules. This retrospective study enrolled 58 consecutive stage IA pulmona...